Benzopyrans, biphenyls and xanthones from the root of Garcinia linii and their activity against Mycobacterium tuberculosis

被引：39

作者：

Chen, JJ ^{[1
]}

Peng, CF

Huang, HY

Chen, IS

机构：

[1] Tajen Univ, Dept Pharm, Pingtung 907, Taiwan

[2] Kaohsiung Med Univ, Fac Biomed Lab Sci, Kaohsiung, Taiwan

[3] Kaohsiung Med Univ, Grad Inst Nat Prod, Kaohsiung, Taiwan

来源：

PLANTA MEDICA | 2006年 / 72卷 / 05期

关键词：

D O I：

10.1055/s-2005-916253

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

A new benzopyran, (S)-3-hydroxygarcibenzopyran, and three new biphenyls, garcibiphenyl C, garcibiphenyl D, garcibipheryl E, together with thirteen known compounds have been additionally isolated from the root of Garcinia linii. The structures of these new compounds were determined through spectral analyses. Among the isolates, 1,7-dihydroxy-3-methoxyxanthone and 1,5-dihydroxy-3-methoxyxanthone showed antitubercular activities with MICs of 3.1 +/- 0.5 and 6.3 +/- 1.0 mu g/mL against Mycobacterium tuberculosis 90 - 221387 in vitro, respectively.

引用

页码：473 / 477

页数：5

共 19 条

[1] CONSTITUENTS OF ISOLONA-MAITLANDII [J].