Two novel α-tocopheroids from the aerial roots of Ficus microcarpa

被引:69
作者
Chiang, YM [1 ]
Kuo, YH [1 ]
机构
[1] Natl Taiwan Univ, Dept Chem, Taipei 10764, Taiwan
关键词
D O I
10.1016/S0040-4039(03)01116-X
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Two novel alpha-tocopheroids, namely alpha-tocospiros A (1) and B (2), together with alpha-tocopherol (3) were isolated from the aerial roots of Ficus microcarpa. Their structures were elucidated by spectral methods. Under basic conditions, compounds 1 and 2 were obtained from alpha-tocoquinon-2,3-oxide (6a and 6b) via a highly stereoselective nucleophilic addition reaction. Reaction and biotransformation mechanisms of 1 and 2 are proposed. (C) 2003 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:5125 / 5128
页数:4
相关论文
共 13 条
[1]   Novel triterpenoids from the aerial roots of Ficus microcarpa [J].
Chiang, YM ;
Kuo, YH .
JOURNAL OF ORGANIC CHEMISTRY, 2002, 67 (22) :7656-7661
[2]   Taraxastane-type triterpenes from the aerial roots of Ficus microcarpa [J].
Chiang, YM ;
Kuo, YH .
JOURNAL OF NATURAL PRODUCTS, 2000, 63 (07) :898-901
[3]   New cyclopropyl-triterpenoids from the aerial roots of Ficus microcarpa [J].
Chiang, YM ;
Su, JK ;
Liu, YH ;
Kuo, YH .
CHEMICAL & PHARMACEUTICAL BULLETIN, 2001, 49 (05) :581-583
[4]   DYE-SENSITIZED PHOTOOXIDATION OF ALPHA-TOCOPHEROL [J].
GRAMS, GW ;
INGLETT, GE ;
ESKINS, K .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1972, 94 (03) :866-&
[5]  
GRAMS WG, 1971, TETRAHEDRON LETT, V12, P4823
[6]  
HIGA M, 1996, B COLL SCI U RYUKYUS, V62, P45
[7]  
HIGA M, 1987, B COLL SCI U RYUKYUS, V13, P75
[8]  
Kitajima J, 1998, CHEM PHARM BULL, V46, P1647, DOI 10.1248/cpb.46.1647
[9]  
Kuo YH, 1999, CHEM PHARM BULL, V47, P498, DOI 10.1248/cpb.47.498
[10]   Constituents of the bark of Ficus microcarpa Lf [J].
Kuo, YH ;
Li, YC .
JOURNAL OF THE CHINESE CHEMICAL SOCIETY, 1997, 44 (03) :321-325