In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States

被引:107
作者
Ge, Yigong [1 ]
Biek, Donald [1 ]
Talbot, George H. [1 ]
Sahm, Daniel F. [2 ]
机构
[1] Cerexa Inc, Alameda, CA USA
[2] Eurofins Medinet, Herndon, VA USA
关键词
D O I
10.1128/AAC.00149-08
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
This study evaluated the in vitro activity of ceftaroline, a novel cephalosporin with broad-spectrum activity against gram-negative and -positive pathogens, against 4,151 recent clinical isolates collected in the United States. Ceftaroline was very potent against bacteria found in community- and hospital-acquired infections, including methicillin-resistant Staphylococcus aureus, multidrug-resistant Streptococcus pneumoniae, and common Enterobacteriaceae spp.
引用
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页码:3398 / 3407
页数:10
相关论文
共 27 条
[1]  
[Anonymous], M100S16 CLSI
[2]  
[Anonymous], 2016, M45 CLSI
[3]   Genome and virulence determinants of high virulence community-acquired MRSA [J].
Baba, T ;
Takeuchi, F ;
Kuroda, M ;
Yuzawa, H ;
Aoki, K ;
Oguchi, A ;
Nagai, Y ;
Iwama, N ;
Asano, K ;
Naimi, T ;
Kuroda, H ;
Cui, L ;
Yamamoto, K ;
Hiramatsu, K .
LANCET, 2002, 359 (9320) :1819-1827
[4]  
Baron EJ, 2007, MANUAL OF CLINICAL MICROBIOLOGY, 9TH ED, P1
[5]   COMMUNITY-ACQUIRED PNEUMONIA [J].
BARTLETT, JG ;
MUNDY, LM .
NEW ENGLAND JOURNAL OF MEDICINE, 1995, 333 (24) :1618-1624
[6]   Infection control - A problem for patient safety [J].
Burke, JP .
NEW ENGLAND JOURNAL OF MEDICINE, 2003, 348 (07) :651-656
[7]  
*CDCP, 2005, ACT BACT COR SURV AB
[8]  
Centers for Disease Control and Prevention (CDC), 2007, ACT BACT COR SURV AB
[9]   Increasing ceftriaxone resistance and multiple alterations of penicillin-binding proteins among penicillin-resistant Streptococcus pneumoniae isolates in Taiwan [J].
Chiu, Cheng-Hsun ;
Su, Lin-Hui ;
Huang, Yhu-Chering ;
Lai, Jui-Chia ;
Chen, Hsiu-Ling ;
Wu, Tsu-Lan ;
Lin, Tzou-Yien .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2007, 51 (09) :3404-3406
[10]  
Clinical and Laboratory Standards Institute, 2007, METH DIL ANT SUSC TE