Reproductive experience and activation of maternal memory

被引：52

作者：

Scanlan, Victoria F. ^{[1
]}

Byrnes, Elizabeth M. ^{[1
]}

Bridges, Robert S. ^{[1
]}

机构：

[1] Tufts Univ, Dept Biomed Sci, Cummings Sch Vet Med, North Grafton, MA 01536 USA

来源：

BEHAVIORAL NEUROSCIENCE | 2006年 / 120卷 / 03期

关键词：

amygdala; nucleus accumbens; c-Fos immunohistochemistry; elevated plus-maze; maternal experience;

D O I：

10.1037/0735-7044.120.3.676

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

The maternal and neurobiological responses of biological mothers and pup-induced maternal virgin rats were compared 55 and 80 days after an initial 2-day maternal experience. When tested for home cage responsiveness after prolonged isolation from young, the biological, primiparous rats displayed shorter maternal latencies. Primiparous females tested in the presence of pups on the elevated plus-maze displayed increased exploration of the open arms and increased c-Fos expression in the cortical nucleus of the amygdala. Pup exposure and parity also enhanced activation of the nucleus accumbens shell and medial nucleus of the amygdala, respectively. Therefore, although both nulliparous and primiparous rats retain a maternal memory for a prolonged time, the memory and neurochemical response appear stronger in primiparous mothers.

引用

页码：676 / 686

页数：11

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