学术探索
学术期刊
新闻热点
数据分析
智能评审

Evolution of anticancer drug discovery and the role of cell-based screening

被引：61
作者：
Balis, FM [1 ]
机构：
[1] NCI, Pediat Oncol Branch, Ctr Canc Res, NIH, Bethesda, MD 20892 USA
来源：
JOURNAL OF THE NATIONAL CANCER INSTITUTE | 2002年 / 94卷 / 02期
关键词：
D O I：
10.1093/jnci/94.2.78
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：78 / 79
页数：2
相关论文
共 19 条
  • [1] Drug discovery: A historical perspective
    Drews, J
    [J]. SCIENCE, 2000, 287 (5460) : 1960 - 1964
  • [2] Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the philadelphia chromosome.
    Druker, BJ
    Sawyers, CL
    Kantarjian, H
    Resta, DJ
    Reese, SF
    Ford, JM
    Capdeville, R
    Talpaz, M
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2001, 344 (14) : 1038 - 1042
  • [3] Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia.
    Druker, BJ
    Talpaz, M
    Resta, DJ
    Peng, B
    Buchdunger, E
    Ford, JM
    Lydon, NB
    Kantarjian, H
    Capdeville, R
    Ohno-Jones, S
    Sawyers, CL
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2001, 344 (14) : 1031 - 1037
  • [4] Lessons learned from the development of an Abl tyrosine kinase inhibitor for chronic myelogenous leukemia
    Druker, BJ
    Lydon, NB
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 2000, 105 (01) : 3 - 7
  • [5] Cell-based assays for identification of novel double-strand break-inducing agents
    Dunstan, HM
    Ludlow, C
    Goehle, S
    Cronk, M
    Szankasi, P
    Evans, DRH
    Simon, JR
    Lamb, JR
    [J]. JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2002, 94 (02): : 88 - 94
  • [6] Mechanism-based target identification and drug discovery in cancer research
    Gibbs, JB
    [J]. SCIENCE, 2000, 287 (5460) : 1969 - 1973
  • [7] Anticancer drug targets: growth factors and growth factor signaling
    Gibbs, JB
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 2000, 105 (01) : 9 - 13
  • [8] Integrating genetic approaches into the discovery of anticancer drugs
    Hartwell, LH
    Szankasi, P
    Roberts, CJ
    Murray, AW
    Friend, SH
    [J]. SCIENCE, 1997, 278 (5340) : 1064 - 1068
  • [9] Choosing anticancer drug targets in the postgenomic era
    Kaelin, WG
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 1999, 104 (11) : 1503 - 1506
  • [10] FEASIBILITY OF A HIGH-FLUX ANTICANCER DRUG SCREEN USING A DIVERSE PANEL OF CULTURED HUMAN TUMOR-CELL LINES
    MONKS, A
    SCUDIERO, D
    SKEHAN, P
    SHOEMAKER, R
    PAULL, K
    VISTICA, D
    HOSE, C
    LANGLEY, J
    CRONISE, P
    VAIGROWOLFF, A
    GRAYGOODRICH, M
    CAMPBELL, H
    MAYO, J
    BOYD, M
    [J]. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1991, 83 (11) : 757 - 766
12