Metal-on-metal joint bearings and hematopoetic malignancy A review

被引：15

作者：

Wagner, Philippe ^{[1
]}

Olsson, Hakan ^{[2
]}

Ranstam, Jonas ^{[1
]}

Robertsson, Otto ^{[1
]}

Zheng, Ming Hao ^{[3
]}

Lidgren, Lars ^{[1
]}

机构：

[1] Lund Univ, Dept Orthoped, Clin Sci Lund, Lund, Sweden

[2] Lund Univ, Dept Oncol, Clin Sci Lund, Lund, Sweden

[3] Univ Western Australia, Ctr Orthopaed Res, Nedlands, WA 6009, Australia

来源：

ACTA ORTHOPAEDICA | 2012年 / 83卷 / 06期

关键词：

TOTAL HIP-ARTHROPLASTY; TOTAL KNEE ARTHROPLASTY; RHEUMATOID-ARTHRITIS; SURFACE REPLACEMENT; POLYETHYLENE WEAR; CANCER INCIDENCE; MEDICAL DEVICES; FEMORAL-HEAD; FOLLOW-UP; RISK;

D O I：

10.3109/17453674.2012.747055

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

100224 [整形外科学];

摘要：

This is a review of the hip arthroplasty era. We concentrate on new metal bearings, surface replacements, and the lessons not learned, and we highlight recent reports on malignancies and joint implants. A low incidence of blood malignancies has been found in bone marrow taken at prosthetic surgery. The incidence is increased after replacement with knee implants that release very low systemic levels of metal ions. A carcinogenic effect of the high levels of metal ions released by large metal-on-metal implants cannot be excluded. Ongoing Swedish implant registry studies going back to 1975 can serve as a basis for evaluation of this risk.

引用

页码：553 / 558

页数：6

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