Silver as Antibacterial Agent: Ion, Nanoparticle, and Metal

被引：1889

作者：

Chernousova, Svitlana ^{[1
,2
]}

Epple, Matthias ^{[1
,2
]}

机构：

[1] Univ Duisburg Essen, Inst Inorgan Chem, D-45117 Essen, Germany

[2] Univ Duisburg Essen, Ctr Nanointegrat Duisburg Essen CeNIDE, D-45117 Essen, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2013年 / 52卷 / 06期

关键词：

antibacterial action; nanoparticles; silver; toxicity; BOVINE SERUM-ALBUMIN; IN-VITRO; PARTICLE-SIZE; INORGANIC NANOPARTICLES; ANTIMICROBIAL ACTIVITY; COATED MEGAPROSTHESES; SULFIDE NANOPARTICLES; ELECTRON-MICROSCOPY; ESCHERICHIA-COLI; DISSOLVED SILVER;

D O I：

10.1002/anie.201205923

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The antibacterial action of silver is utilized in numerous consumer products and medical devices. Metallic silver, silver salts, and also silver nanoparticles are used for this purpose. The state of research on the effect of silver on bacteria, cells, and higher organisms is summarized. It can be concluded that the therapeutic window for silver is narrower than often assumed. However, the risks for humans and the environment are probably limited. Silver shield: Silver is used in different forms as an antibacterial agent. Earlier, sparingly soluble silver salts were predominantly used, but today, silver nanoparticles (see picture for an SEM image of cubic silver nanoparticles) are gaining increasing importance. As silver is also toxic towards mammalian cells, there is the question of the therapeutic window in the cases of consumer products and medical devices. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：1636 / 1653

页数：18

共 235 条

[41] Influence of copper ions on the viability and cytotoxicity of Pseudomonas aeruginosa under conditions relevant to drinking water environments [J].