Distribution of phosphoglycerate mutase isozymes in rat, rabbit and human tissues

被引：20

作者：

Durany, N ^{[1
]}

Carreras, J ^{[1
]}

机构：

[1] UNIV BARCELONA,FAC MED,UNITAT BIOQUIM,E-08028 BARCELONA,SPAIN

来源：

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY | 1996年 / 114卷 / 02期

关键词：

adenylate kinase; 2,3-bisphosphoglycerate phosphatase; phosphoglycerate mutase; human; rabbit and rat tissue isozyme distribution;

D O I：

10.1016/0305-0491(95)02135-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The distribution of phosphoglycerate mutase isozymes (types MM, MB and BE) in rat, rabbit and human tissues has been studied by electrophoresis on cellulose acetate and by highly-resolutive ion exchange chromatography. In the three species, muscle is the tissue with higher phosphoglycerate mutase activity. Heart is the only tissue with the three phosphoglycerate mutase isozymes in substantial amounts. Skeletal muscle contains mostly type MM isozyme and the other tissues possess almost exclusively type BE isozyme. Even in the presence of inhibitors, adenylate kinase can interfere with the staining reactions when large samples are analyzed and a long period of incubation is required.

引用

页码：217 / 223

页数：7