National and regional assessment of the antibacterial soap market: A step toward determining the impact of prevalent antibacterial soaps

被引:108
作者
Perencevich, EN
Wong, MT
Harris, AD
机构
[1] Beth Israel Deaconess Med Ctr, Div Infect Dis, Dept Med, Boston, MA 02215 USA
[2] Univ Maryland, Dept Epidemiol & Prevent Med, Div Healthcare Outcomes Res, Baltimore, MD 21201 USA
关键词
D O I
10.1067/mic.2001.115469
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Background: Consumer antibacterial soaps contain triclosan or triclocarban. No scientific data have been published to suggest that the use of antibacterial agents in household products prevents infection, and triclosan resistance mechanisms have recently been identified. Little data are available regarding the prevalence of antibacterial agents contained in consumer soaps. Methods: In a physician-performed survey of 23 stores in 10 states from December 1999 to April 2000, investigators determined the number of national brand liquid and bar soaps and percent of each containing antibacterial agents sold at national chain, regional grocery, and Internet stores. Results: Antibacterial agents were present in 76% of liquid soaps and 29% of bar soaps available nationally. There were no differences found between national, regional, and Internet stores. Conclusion: Overall, 45% of surveyed soaps contain antibacterial agents. With limited documented benefits and experimental laboratory evidence suggesting possible adverse effects on the emergence of antimicrobial resistance, consumer antibacterial use of this magnitude should be questioned.
引用
收藏
页码:281 / 283
页数:3
相关论文
共 16 条
[1]   Broad spectrum antimicrobial biocides target the FabI component of fatty acid synthesis [J].
Heath, RJ ;
Yu, YT ;
Shapiro, MA ;
Olson, E ;
Rock, CO .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (46) :30316-30320
[2]   Inhibition of the Staphylococcus aureus NADPH-dependent enoyl-acyl carrier protein reductase by triclosan and hexachlorophene [J].
Heath, RJ ;
Li, J ;
Roland, GE ;
Rock, CO .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (07) :4654-4659
[3]   Mechanism of triclosan inhibition of bacterial fatty acid synthesis [J].
Heath, RJ ;
Rubin, JR ;
Holland, DR ;
Zhang, EL ;
Snow, ME ;
Rock, CO .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (16) :11110-11114
[4]   Characterization of Pseudomonas aeruginosa Enoyl-Acyl carrier protein reductase (FabI):: a target for the antimicrobial triclosan and its role in acylated homoserine lactone synthesis [J].
Hoang, TT ;
Schweizer, HP .
JOURNAL OF BACTERIOLOGY, 1999, 181 (17) :5489-5497
[5]   Control of an outbreak of an epidemic methicillin-resistant Staphylococcus aureus also resistant to mupirocin [J].
Irish, D ;
Eltringham, I ;
Teall, A ;
Pickett, H ;
Farelly, H ;
Reith, S ;
Woodford, N ;
Cookson, B .
JOURNAL OF HOSPITAL INFECTION, 1998, 39 (01) :19-26
[6]   Triclosan: A review of effectiveness and safety in health care settings [J].
Jones, RD ;
Jampani, HB ;
Newman, JL ;
Lee, AS .
AMERICAN JOURNAL OF INFECTION CONTROL, 2000, 28 (02) :184-196
[7]   Molecular basis of triclosan activity [J].
Levy, CW ;
Roujeinikova, A ;
Sedelnikova, S ;
Baker, PJ ;
Stuitje, AR ;
Slabas, AR ;
Rice, DW ;
Rafferty, JB .
NATURE, 1999, 398 (6726) :383-384
[8]   Efficacy of triclosan - Reply [J].
Levy, SB ;
McMurry, LM .
AMERICAN JOURNAL OF INFECTION CONTROL, 1999, 27 (01) :73-74
[9]   Antiseptics and disinfectants: Activity, action, and resistance [J].
McDonnell, G ;
Russell, AD .
CLINICAL MICROBIOLOGY REVIEWS, 1999, 12 (01) :147-+
[10]   Triclosan targets lipid synthesis [J].
McMurry, LM ;
Oethinger, M ;
Levy, SB .
NATURE, 1998, 394 (6693) :531-532