Frontal-subcortical circuits: The anatomic basis of executive, social and motivated behaviors

被引：170

作者：

Masterman, DL

Cummings, JL

机构：

[1] UNIV CALIF LOS ANGELES,SCH MED,DEPT NEUROL,LOS ANGELES,CA

[2] UNIV CALIF LOS ANGELES,SCH MED,DEPT PSYCHIAT & BIOBEHAV SCI,LOS ANGELES,CA

[3] W LOS ANGELES VET AFFAIRS MED CTR,PSYCHIAT SERV,BEHAV NEUROSCI SECT,LOS ANGELES,CA

来源：

JOURNAL OF PSYCHOPHARMACOLOGY | 1997年 / 11卷 / 02期

关键词：

dopamine; frontal-subcortical circuits; matrix; receptors; striatum; striosomes;

D O I：

10.1177/026988119701100203

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A series of discrete, parallel frontal-subcortical circuits have been demonstrated to link specific areas of the frontal lobe to areas within the basal ganglia and thalamus. A variety of circuit-specific behaviors can be described involving the dorsolateral prefrontal, orbitofrontal and anterior cingulate circuits. Interruptions or imbalance occurring at various levels within these closed looped circuits is felt to underlie the characteristic behavioral patterns seen. The intricate neurochemical arrangement of the striatum and the complex neurotransmitter interactions that occur within these key subcortical structures form the basis for modulatory influences that can affect these circuits.

引用

页码：107 / 114

页数：8