Intellectual Property Rights and Innovation: Evidence from the Human Genome

被引:186
作者
Williams, Heidi L. [1 ,2 ]
机构
[1] MIT, Cambridge, MA 02139 USA
[2] Natl Bur Econ Res, Cambridge, MA 02138 USA
基金
美国国家科学基金会;
关键词
KNOWLEDGE; PATENTS; ECONOMICS; PROJECT;
D O I
10.1086/669706
中图分类号
F [经济];
学科分类号
02 ;
摘要
Do intellectual property (IP) rights on existing technologies hinder subsequent innovation? Using newly collected data on the sequencing of the human genome by the public Human Genome Project and the private firm Celera, this paper estimates the impact of Celera's gene-level IP on subsequent innovation. Across a range of empirical specifications, I document evidence that Celera's IP led to reductions in subsequent scientific research and product development on the order of 20-30 percent. These results suggest that Celera's short-term IP had persistent negative effects on subsequent innovation relative to a counterfactual of Celera genes having always been in the public domain.
引用
收藏
页码:1 / 27
页数:27
相关论文
共 46 条
[1]   Academic freedom, private-sector focus, and the process of innovation [J].
Aghion, Philippe ;
Dewatripont, Mathias ;
Stein, Jeremy C. .
RAND JOURNAL OF ECONOMICS, 2008, 39 (03) :617-635
[2]  
Anand BN, 2000, J IND ECON, V48, P103
[3]  
[Anonymous], 1962, RATE DIRECTION INVEN, DOI DOI 10.1521/IJGP.2006.56.2.191
[4]   Holdup and licensing of cumulative innovations with private information [J].
Bessen, J .
ECONOMICS LETTERS, 2004, 82 (03) :321-326
[5]   Effects of patents and licenses on the provision of clinical genetic testing services [J].
Cho, MK ;
Illangasekare, S ;
Weaver, MA ;
Leonard, DGB ;
Merz, JF .
JOURNAL OF MOLECULAR DIAGNOSTICS, 2003, 5 (01) :3-8
[6]  
Cohen W, 2008, INNOVATION POLICY EC, V8
[7]   A NEW 5-YEAR PLAN FOR THE UNITED-STATES HUMAN GENOME PROJECT [J].
COLLINS, F ;
GALAS, D .
SCIENCE, 1993, 262 (5130) :43-46
[8]   New goals for the US Human Genome Project: 1998-2003 [J].
Collins, FS ;
Patrinos, A ;
Jordan, E ;
Chakravarti, A ;
Gesteland, R ;
Walters, L ;
Fearon, E ;
Hartwelt, L ;
Langley, CH ;
Mathies, RA ;
Olson, M ;
Pawson, AJ ;
Pollard, T ;
Williamson, A ;
Wold, B ;
Buetow, K ;
Branscomb, E ;
Capecchi, M ;
Church, G ;
Garner, H ;
Gibbs, RA ;
Hawkins, T ;
Hodgson, K ;
Knotek, M ;
Meisler, M ;
Rubin, GM ;
Smith, LM ;
Smith, RF ;
Westerfield, M ;
Clayton, EW ;
Fisher, NL ;
Lerman, CE ;
McInerney, JD ;
Nebo, W ;
Press, N ;
Valle, D .
SCIENCE, 1998, 282 (5389) :682-689
[9]  
Cook-Deegan Robert., 1994, The Gene Wars: Science, Politics, and the Human Genome
[10]   Genomics in the public domain: strategy and policy [J].
Eisenberg, RS .
NATURE REVIEWS GENETICS, 2000, 1 (01) :70-74