The UCSC Genome Browser database: 2017 update

被引：237

作者：

Tyner, Cath ^{[1
]}

Barber, Galt P. ^{[1
]}

Casper, Jonathan ^{[1
]}

Clawson, Hiram ^{[1
]}

Diekhans, Mark ^{[1
]}

Eisenhart, Christopher ^{[1
]}

Fischer, Clayton M. ^{[1
]}

Gibson, David ^{[1
]}

Gonzalez, Jairo Navarro ^{[1
]}

Guruvadoo, Luvina ^{[1
]}

Haeussler, Maximilian ^{[1
]}

Heitner, Steve ^{[2
]}

Hinrichs, Angie S. ^{[1
]}

Karolchik, Donna ^{[1
]}

Lee, Brian T. ^{[1
]}

Lee, Christopher M. ^{[1
]}

Nejad, Parisa ^{[1
]}

Raney, Brian J. ^{[1
]}

Rosenbloom, Kate R. ^{[1
]}

Speir, Matthew L. ^{[1
]}

Villarreal, Chris ^{[1
]}

Vivian, John ^{[1
]}

Zweig, Ann S. ^{[1
]}

Haussler, David ^{[1
,3
]}

Kuhn, Robert M. ^{[1
]}

Kent, W. James ^{[1
]}

机构：

[1] Univ Calif Santa Cruz, Genom Inst, Santa Cruz, CA 95064 USA

[2] Emory Univ, Sch Med, Atlanta, GA 30322 USA

[3] Univ Calif Santa Cruz, Howard Hughes Med Inst, Santa Cruz, CA 95064 USA

来源：

NUCLEIC ACIDS RESEARCH | 2017年 / 45卷 / D1期

关键词：

ENCODE DATA; ANNOTATION; SEQUENCE; MAP;

D O I：

10.1093/nar/gkw1134

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Since its 2001 debut, the University of California, Santa Cruz (UCSC) Genome Browser (http://genome.ucsc.edu/) team has provided continuous support to the international genomics and biomedical communities through a web-based, open source platform designed for the fast, scalable display of sequence alignments and annotations landscaped against a vast collection of quality reference genome assemblies. The browser's publicly accessible databases are the backbone of a rich, integrated bioinformatics tool suite that includes a graphical interface for data queries and downloads, alignment programs, command-line utilities and more. This year's high-lights include newly designed home and gateway pages; a new `multi-region' track display configuration for exon-only, gene-only and custom regions visualization; new genome browsers for three species (brown kiwi, crab-eatingmacaque and Malayan flying lemur); eight updated genome assemblies; extended support for new data types such as CRAM, RNA-seq expression data and long-range chromatin interaction pairs; and the unveiling of a new supported mirror site in Japan.

引用

页码：D626 / D634

页数：9

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