Noninvasive quantification of rCBF using positron emission tomography

被引：24

作者：

Watabe, H

Itoh, M

Cunningham, V

Lammertsma, AA

Bloomfield, P

Mejia, M

Fujiwara, T

Jones, AKP

Jones, T

Nakamura, T

机构：

[1] TOHOKU UNIV,CTR CYCLOTRON & RADIOISOTOPE,SENDAI,MIYAGI 980,JAPAN

[2] HAMMERSMITH HOSP,MRC,CYCLOTRON UNIT,LONDON W12 0HS,ENGLAND

[3] HOPE HOSP,CTR RHEUMAT DIS,MANCHESTER,LANCS,ENGLAND

来源：

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM | 1996年 / 16卷 / 02期

关键词：

regional cerebral blood flow; positron emission tomography; noninvasive quantification;

D O I：

10.1097/00004647-199603000-00017

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This study proposes a new method for the pixel-by-pixel quantification of regional CBF (rCBF) with positron emission tomography and (H2O)-O-15 by using a reference tissue region. No arterial blood is required. Simulation studies revealed that the calculation of rCBF was fairly stable provided that the frame time was relatively short compared with total scan time. In practice, calculated CBF images correlated significantly with those obtained with the dynamic/integral method. Because the method accurately detects changes in CBF, it is particularly suitable for brain activation studies.

引用

页码：311 / 319

页数：9

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