Solid-phase synthesis of benzoxazoles via Mitsunobu reaction

被引：43

作者：

Wang, FJ

Hauske, JR

机构：

[1] Department of Drug Discovery, Sepracor Inc., Marlborough, MA 01752

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 37期

关键词：

D O I：

10.1016/S0040-4039(97)01527-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2-Amidophenol attached to a solid support can be converted corresponding benzoxazole by treatment with triphenylphosphine and azodicarboxylate in THF at room temperature in high yield and purity. (C) 1997 Elsevier Science Ltd.

引用

页码：6529 / 6532

页数：4

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