Severe preeclampsia at <25 weeks of gestation:: Maternal and neonatal outcomes

被引:28
作者
Jenkins, SM [1 ]
Head, BB [1 ]
Hauth, JC [1 ]
机构
[1] Univ Alabama, Dept Obstet & Gynecol, Birmingham, AL 35294 USA
关键词
preeclampsia; second trimester; treatment;
D O I
10.1067/mob.2002.122290
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
OBJECTIVE: The purpose of this study was to determine maternal and neonatal outcomes of women who were delivered because of severe preeclampsia before 25 weeks of gestation. STUDY DESIGN: We used a computerized database to identify 3800 women with preeclampsia among 35,937 deliveries from 1991 to 1997. Of these, 39 women (1%) with severe preeclampsia were delivered before 25 weeks of gestation. We abstracted outcomes in these women and their newborns. RESULTS: All 39 women had severe preeclampsia as defined by clinical and/or laboratory criteria. Thirty-three of the 39 women had severe-range hypertension. Twenty-one women (54%) experienced morbidity that included abruptio placentae (n = 5), HELLP (hemolysis, elevated liver enzymes, and low platelet count) syndrome (n = 9), renal insufficiency (n = 5), and eclampsia (n = 3). No women required dialysis or intensive care unit admission, and none of the women died. All maternal morbidities reversed after delivery. Twenty-two infants (55%) were live-born. Only 4 infants (10%) survived, all with severe handicaps. CONCLUSION: In women with severe preeclampsia before 25 weeks of gestation, delivery is associated with minimal short-term maternal morbidities, although neonatal morbidity and death are appreciable.
引用
收藏
页码:790 / 795
页数:6
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