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Targeting c-kit mutations in solid tumors:: Scientific rationale and novel therapeutic options

被引：134
作者：
Demetri, GD [1 ]
机构：
[1] Harvard Univ, Sch Med, Dana Farber Canc Inst, Dept Adult Oncol, Boston, MA 02115 USA
来源：
SEMINARS IN ONCOLOGY | 2001年 / 28卷 / 05期
关键词：
D O I：
10.1053/sonc.2001.29181
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：19 / 26
页数：8
相关论文
共 41 条
  • [1] Akin C, 2000, BLOOD, V96, p747A
  • [2] [Anonymous], 2001, P AM SOC CLIN ONCOL
  • [3] Appelman H D, 1990, Monogr Pathol, P220
  • [4] Blanke CD, 2001, P AM SOC CLIN ONCOL, p1a
  • [5] Buchdunger E, 1996, CANCER RES, V56, P100
  • [6] Buchdunger E, 2000, J PHARMACOL EXP THER, V295, P139
  • [7] Two hundred gastrointestinal stromal tumors - Recurrence patterns and prognostic factors for survival
    DeMatteo, RP
    Lewis, JJ
    Leung, D
    Mudan, SS
    Woodruff, JM
    Brennan, MF
    [J]. ANNALS OF SURGERY, 2000, 231 (01) : 51 - 58
  • [8] Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the philadelphia chromosome.
    Druker, BJ
    Sawyers, CL
    Kantarjian, H
    Resta, DJ
    Reese, SF
    Ford, JM
    Capdeville, R
    Talpaz, M
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2001, 344 (14) : 1038 - 1042
  • [9] Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells
    Druker, BJ
    Tamura, S
    Buchdunger, E
    Ohno, S
    Segal, GM
    Fanning, S
    Zimmermann, J
    Lydon, NB
    [J]. NATURE MEDICINE, 1996, 2 (05) : 561 - 566
  • [10] Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia.
    Druker, BJ
    Talpaz, M
    Resta, DJ
    Peng, B
    Buchdunger, E
    Ford, JM
    Lydon, NB
    Kantarjian, H
    Capdeville, R
    Ohno-Jones, S
    Sawyers, CL
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2001, 344 (14) : 1031 - 1037
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