DropBot: An open-source digital microfluidic control system with precise control of electrostatic driving force and instantaneous drop velocity measurement

被引:174
作者
Fobel, Ryan [1 ,2 ]
Fobel, Christian [3 ]
Wheeler, Aaron R. [1 ,2 ,4 ]
机构
[1] Univ Toronto, Inst Biomat & Biomed Engn, Toronto, ON M5S 3G9, Canada
[2] Donnelly Ctr Cellular & Biomol Res, Toronto, ON M5S 3E1, Canada
[3] Univ Guelph, Sch Comp Sci, Guelph, ON N1G 2W1, Canada
[4] Univ Toronto, Dept Chem, Toronto, ON M5S 3H6, Canada
基金
加拿大自然科学与工程研究理事会;
关键词
ELECTROWETTING-BASED ACTUATION; PLURONIC ADDITIVES; ON-CHIP; IMPEDANCE;
D O I
10.1063/1.4807118
中图分类号
O59 [应用物理学];
学科分类号
摘要
We introduce DropBot: an open-source instrument for digital microfluidics ( http://microfluidics.utoronto.ca/dropbot). DropBot features two key functionalities for digital microfluidics: (1) real-time monitoring of instantaneous drop velocity (which we propose is a proxy for resistive forces), and (2) application of constant electrostatic driving forces through compensation for amplifier-loading and device capacitance. We anticipate that this system will enhance insight into failure modes and lead to new strategies for improved device reliability, and will be useful for the growing number of users who are adopting digital microfluidics for automated, miniaturized laboratory operation. (C) 2013 AIP Publishing LLC.
引用
收藏
页数:5
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