Repeated implantation failure: clinical approach

被引:272
作者
Simon, Alex [1 ]
Laufer, Neri [1 ]
机构
[1] Hebrew Univ Jerusalem, Hadassah Med Ctr, Dept Obstet & Gynecol, In Vitro Fertilizat Unit, IL-91120 Jerusalem, Israel
关键词
Repeated implantation failure; recurrent implantation failure; RIF; IVF; implantation; ZYGOTE INTRAFALLOPIAN TRANSFER; ENDOMETRIAL RECEPTIVITY; LOCAL INJURY; PREGNANCY; FERTILIZATION; WOMEN; THROMBOPHILIA; EXPRESSION; PREDICTOR; HEPARIN;
D O I
10.1016/j.fertnstert.2012.03.010
中图分类号
R71 [妇产科学];
学科分类号
100211 [妇产科学];
摘要
Successful embryo implantation depends on a well-functioning endometrium as well as a normal healthy embryo. This process might be hampered if either of these variables is defective. Repeated implantation failure (RIF) is diagnosed when good-quality embryos repeatedly fail to implant after transfer in several IVF treatment cycles. The causes of RIF originate with either the mother or the embryo. The authors discuss factors that are associated with RIF and address various treatment options. (Fertil Steril (R) 2012;97:1039-43. (C) 2012 by American Society for Reproductive Medicine.)
引用
收藏
页码:1039 / 1043
页数:5
相关论文
共 44 条
[1]
Endometrial receptivity markers, the journey to successful embryo implantation [J].
Achache, Hanna ;
Revel, Ariel .
HUMAN REPRODUCTION UPDATE, 2006, 12 (06) :731-746
[2]
Interval double transfer improves treatment success in patients with repeated IVF/ET failures [J].
Almog, B. ;
Levin, I. ;
Wagman, I. ;
Kapustiansky, R. ;
Schwartz, T. ;
Mey-Raz, N. ;
Amit, A. ;
Azem, F. .
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS, 2008, 25 (08) :353-357
[3]
Salpingectomy for hydrosalpinx prior to in vitro fertilization [J].
不详 .
FERTILITY AND STERILITY, 2008, 90 :S66-S68
[4]
[Anonymous], [No title captured]
[5]
Dynamic changes in gene expression during human early embryo development: from fundamental aspects to clinical applications [J].
Assou, Said ;
Boumela, Imene ;
Haouzi, Delphine ;
Anahory, Tal ;
Dechaud, Herve ;
De Vos, John ;
Hamamah, Samir .
HUMAN REPRODUCTION UPDATE, 2011, 17 (02) :272-290
[6]
Increased rates of thrombophilia in women with repeated IVF failures [J].
Azem, F ;
Many, A ;
Yovel, I ;
Amit, A ;
Lessing, JB ;
Kupferminc, MJ .
HUMAN REPRODUCTION, 2004, 19 (02) :368-370
[7]
Clinical outcome of intracytoplasmic injection of spermatozoa morphologically selected under high magnification: a prospective randomized study [J].
Balaban, Basak ;
Yakin, Kayhan ;
Alatas, Cengiz ;
Oktem, Ozgur ;
Isiklar, Aycan ;
Urman, Bulent .
REPRODUCTIVE BIOMEDICINE ONLINE, 2011, 22 (05) :472-476
[8]
The role of low-molecular-weight heparin in recurrent implantation failure: a prospective, quasi-randomized, controlled study [J].
Berker, Bulent ;
Taskin, Salih ;
Kahraman, Korhan ;
Taskin, Elif Aylin ;
Atabekoglu, Cem ;
Sonmezer, Murat .
FERTILITY AND STERILITY, 2011, 95 (08) :2499-2502
[9]
Effects and effectiveness of heparin in assisted reproduction [J].
Bohlmann, Michael K. .
JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 2011, 90 (01) :82-90
[10]
Recombinant human leukemia inhibitory factor does not improve implantation and pregnancy outcomes after assisted reproductive techniques in women with recurrent unexplained implantation failure [J].
Brinsden, Peter R. ;
Alam, Veronica ;
de Moustier, Beatrice ;
Engrand, Patrick .
FERTILITY AND STERILITY, 2009, 91 (04) :1445-1447