Measuring women's preferences for breast cancer treatments and BRCA1/BRCA2 testing

被引:27
作者
Cappelli, M
Surh, L
Humphreys, L
Verma, S
Logan, D
Hunter, A
Allanson, J
机构
[1] Childrens Hosp Eastern Ontario, Ottawa, ON K1H 8L1, Canada
[2] Ottawa Reg Canc Ctr, Gen Div, Ottawa, ON K1Y 4K7, Canada
关键词
breast cancer; genetic testing; preferences; quality of life; utility assessment;
D O I
10.1023/A:1013123915272
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
In establishing decision models in the treatment and prevention of breast cancer, it is important to evaluate patients' preferences for such interventions. The objectives of the present study were: (i) to characterize women's preferences for breast cancer treatments and BRCA1/BRCA2 testing, using the rating scale and standard gamble techniques; and (ii) to identify factors associated with these quality of life indices. Data were collected from women with breast cancer (n = 60), high-risk relatives of women with breast cancer (n = 58), and women in the general population (n = 51). Regardless of group membership, participants favoured treatment and prevention options that involved minimal physical invasiveness. Women with breast cancer rated lumpectomy and radiation treatment more highly than high-risk relatives and women in the general population. Preferences did not differ according to participants' intentions to undergo BRCA testing. Age was the only demographic variable associated with health state preferences. These findings hold implications for the application of patient preferences to clinical decision making.
引用
收藏
页码:595 / 607
页数:13
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