The transcriptional regulator BZR1 mediates trade-off between plant innate immunity and growth

被引:174
作者
Lozano-Duran, Rosa [1 ]
Macho, Alberto P. [1 ]
Boutrot, Freddy [1 ]
Segonzac, Cecile [1 ]
Somssich, Imre E. [2 ]
Zipfel, Cyril [1 ]
机构
[1] Sainsbury Lab, Norwich, Norfolk, England
[2] Max Planck Inst Plant Breeding Res, Cologne, Germany
来源
ELIFE | 2013年 / 2卷
基金
英国生物技术与生命科学研究理事会;
关键词
BRASSINOSTEROID SIGNAL-TRANSDUCTION; ARABIDOPSIS-THALIANA; MOLECULAR-PATTERNS; GSK3-LIKE KINASES; RESPONSES; BIOSYNTHESIS; RESISTANCE; EXPRESSION; WRKY40; MUTAGENESIS;
D O I
10.7554/eLife.00983
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The molecular mechanisms underlying the trade-off between plant innate immunity and steroid-mediated growth are controversial. Here, we report that activation of the transcription factor BZR1 is required and sufficient for suppression of immune signaling by brassinosteroids (BR). BZR1 induces the expression of several WRKY transcription factors that negatively control early immune responses. In addition, BZR1 associates with WRKY40 to mediate the antagonism between BR and immune signaling. We reveal that BZR1-mediated inhibition of immunity is particularly relevant when plant fast growth is required, such as during etiolation. Thus, BZR1 acts as an important regulator mediating the trade-off between growth and immunity upon integration of environmental cues.
引用
收藏
页数:15
相关论文
共 55 条
[1]   Brassinosteroids inhibit pathogen-associated molecular pattern-triggered immune signaling independent of the receptor kinase BAK1 [J].
Albrecht, Catherine ;
Boutrot, Freddy ;
Segonzac, Cecile ;
Schwessinger, Benjamin ;
Gimenez-Ibanez, Selena ;
Chinchilla, Delphine ;
Rathjen, John P. ;
de Vries, Sacco C. ;
Zipfel, Cyril .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2012, 109 (01) :303-308
[2]   Genome-wide Insertional mutagenesis of Arabidopsis thaliana [J].
Alonso, JM ;
Stepanova, AN ;
Leisse, TJ ;
Kim, CJ ;
Chen, HM ;
Shinn, P ;
Stevenson, DK ;
Zimmerman, J ;
Barajas, P ;
Cheuk, R ;
Gadrinab, C ;
Heller, C ;
Jeske, A ;
Koesema, E ;
Meyers, CC ;
Parker, H ;
Prednis, L ;
Ansari, Y ;
Choy, N ;
Deen, H ;
Geralt, M ;
Hazari, N ;
Hom, E ;
Karnes, M ;
Mulholland, C ;
Ndubaku, R ;
Schmidt, I ;
Guzman, P ;
Aguilar-Henonin, L ;
Schmid, M ;
Weigel, D ;
Carter, DE ;
Marchand, T ;
Risseeuw, E ;
Brogden, D ;
Zeko, A ;
Crosby, WL ;
Berry, CC ;
Ecker, JR .
SCIENCE, 2003, 301 (5633) :653-657
[3]   A Triple Helix-Loop-Helix/Basic Helix-Loop-Helix Cascade Controls Cell Elongation Downstream of Multiple Hormonal and Environmental Signaling Pathways in Arabidopsis [J].
Bai, Ming-Yi ;
Fan, Min ;
Oh, Eunkyoo ;
Wang, Zhi-Yong .
PLANT CELL, 2012, 24 (12) :4917-4929
[4]   Brassinosteroid, gibberellin and phytochrome impinge on a common transcription module in Arabidopsis [J].
Bai, Ming-Yi ;
Shang, Jian-Xiu ;
Oh, Eunkyoo ;
Fan, Min ;
Bai, Yang ;
Zentella, Rodolfo ;
Sun, Tai-ping ;
Wang, Zhi-Yong .
NATURE CELL BIOLOGY, 2012, 14 (08) :810-U78
[5]   Brassinosteroids modulate the efficiency of plant immune responses to microbe-associated molecular patterns [J].
Belkhadir, Youssef ;
Jaillais, Yvon ;
Epple, Petra ;
Balsemao-Pires, Emilia ;
Dangl, Jeffery L. ;
Chory, Joanne .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2012, 109 (01) :297-302
[6]   Differential innate immune signalling via Ca2+ sensor protein kinases [J].
Boudsocq, Marie ;
Willmann, Matthew R. ;
McCormack, Matthew ;
Lee, Horim ;
Shan, Libo ;
He, Ping ;
Bush, Jenifer ;
Cheng, Shu-Hua ;
Sheen, Jen .
NATURE, 2010, 464 (7287) :418-U116
[7]   Trichoderma-Plant Root Colonization: Escaping Early Plant Defense Responses and Activation of the Antioxidant Machinery for Saline Stress Tolerance [J].
Brotman, Yariv ;
Landau, Udi ;
Cuadros-Inostroza, Alvaro ;
Takayuki, Tohge ;
Fernie, Alisdair R. ;
Chet, Ilan ;
Viterbo, Ada ;
Willmitzer, Lothar .
PLOS PATHOGENS, 2013, 9 (03)
[8]   Photoreceptor Signaling Networks in Plant Responses to Shade [J].
Casal, Jorge J. .
ANNUAL REVIEW OF PLANT BIOLOGY, VOL 64, 2013, 64 :403-427
[9]   Benefits of brassinosteroid crosstalk [J].
Choudhary, Sikander Pal ;
Yu, Jing-Quan ;
Yamaguchi-Shinozaki, Kazuko ;
Shinozaki, Kazuo ;
Lam-Son Phan Tran .
TRENDS IN PLANT SCIENCE, 2012, 17 (10) :594-605
[10]   Chemical Inhibition of a Subset of Arabidopsis thaliana GSK3-like Kinases Activates Brassinosteroid Signaling [J].
De Rybel, Bert ;
Audenaert, Dominique ;
Vert, Gregory ;
Rozhon, Wilfried ;
Mayerhofer, Juliane ;
Peelman, Frank ;
Coutuer, Silvie ;
Denayer, Tinneke ;
Jansen, Leentje ;
Nguyen, Long ;
Vanhoufte, Isabelle ;
Beemster, Gerrit T. S. ;
Vleminckx, Kris ;
Jonak, Claudia ;
Chory, Joanne ;
Inze, Dirk ;
Russinova, Eugenia ;
Beeckman, Tom .
CHEMISTRY & BIOLOGY, 2009, 16 (06) :594-604