Cyclosporine-related reversible posterior leukoencephalopathy: MRI

被引：66

作者：

Jarosz, JM ^{[1
]}

Howlett, DC ^{[1
]}

Cox, TCS ^{[1
]}

Bingham, JB ^{[1
]}

机构：

[1] UMDS & GUYS & ST THOMAS HOSP NHS TRUST,MAGNET RESONANCE CTR,LONDON SE1 9RT,ENGLAND

来源：

NEURORADIOLOGY | 1997年 / 39卷 / 10期

关键词：

leukoencephalopathy; cyclosporine; magnetic resonance angiography; organ transplants;

D O I：

10.1007/s002340050492

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Three patients aged 48, 11 and 40 years, two of whom were recent recipients of renal transplants and one of a bone marrow transplant, developed seizures, with cortical blindness in two cases. All were immunosuppressed with cyclosporine and were hypertensive at the onset of symptoms. MRI showed predominantly posterior signal changes in all three cases. The abnormalities were more conspicuous on fast FLAIR images than on conventional T2-weighted spin-echo images.

引用

页码：711 / 715

页数：5

共 16 条

[1] CYCLOSPORINE-ASSOCIATED CENTRAL NERVOUS-SYSTEM TOXICITY AFTER ALLOGENEIC BONE-MARROW TRANSPLANTATION [J].

ATKINSON, K ;

BIGGS, J ;

DARVENIZA, P ;

BOLAND, J ;

CONCANNON, A ;

DODDS, A .

TRANSPLANTATION, 1984, 38 (01) :34-37

[2]

BOOGAERTS MA, 1982, LANCET, V2, P1216

[3] CENTRAL-NERVOUS-SYSTEM TOXICITY AFTER LIVER-TRANSPLANTATION - THE ROLE OF CYCLOSPORINE AND CHOLESTEROL [J].

DEGROEN, PC ;

AKSAMIT, AJ ;

RAKELA, J ;

FORBES, GS ;

KROM, RAF .

NEW ENGLAND JOURNAL OF MEDICINE, 1987, 317 (14) :861-866

[4] Encephalopathy following heart-lung transplantation [J].

Goodman, JM ;

Kuzma, B .

SURGICAL NEUROLOGY, 1996, 46 (02) :157-157

[5] USE OF FLUID ATTENUATED INVERSION RECOVERY (FLAIR) PULSE SEQUENCES IN MRI OF THE BRAIN [J].

HAJNAL, JV ;

BRYANT, DJ ;

KASUBOSKI, L ;

PATTANY, PM ;

DECOENE, B ;

LEWIS, PD ;

PENNOCK, JM ;

OATRIDGE, A ;

YOUNG, IR ;

BYDDER, GM .

JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 1992, 16 (06) :841-844

[6] A reversible posterior leukoencephalopathy syndrome [J].

Hinchey, J ;

Chaves, C ;

Appignani, B ;

Breen, J ;

Pao, L ;

Wang, A ;

Pessin, MS ;

Lamy, C ;

Mas, JL ;

Caplan, LR .

NEW ENGLAND JOURNAL OF MEDICINE, 1996, 334 (08) :494-500

[7] TRANSIENT CORTICAL BLINDNESS AND BIOCCIPITAL BRAIN-LESIONS IN 2 PATIENTS WITH ACUTE INTERMITTENT PORPHYRIA [J].

KUPFERSCHMIDT, H ;

BONT, A ;

SCHNORF, H ;

LANDIS, T ;

WALTER, E ;

PETER, J ;

KRAHENBUHL, S ;

MEIER, PJ .

ANNALS OF INTERNAL MEDICINE, 1995, 123 (08) :598-600

[8] CYCLOSPORINE-ASSOCIATED CENTRAL NEUROTOXICITY AFTER HEART-TRANSPLANTATION [J].

MCMANUS, RP ;

OHAIR, DP ;

SCHWEIGER, J ;

BEITZINGER, J ;

SIEGEL, R .

ANNALS OF THORACIC SURGERY, 1992, 53 (02) :326-327

[9] CYCLOSPORINE-A-INDUCED NEUROTOXICITY [J].

MONTEIRO, L ;

ALMEIDAPINTO, J ;

ROCHA, N ;

LOPES, G ;

ROCHA, J .

BRITISH JOURNAL OF RADIOLOGY, 1993, 66 (783) :271-272

[10]

NORDAL KP, 1985, LANCET, V2, P153

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