Cybrid human embryos - warranting opportunities to augment embryonic stem cell research

被引:3
作者
Fulka, Josef, Jr. [1 ]
Fulka, Helena [1 ,2 ]
St John, Justin [2 ]
Galli, Cesare [3 ,4 ]
Lazzari, Giovanna [4 ]
Lagutina, Irina [4 ]
Fulka, Josef [5 ]
Loi, Pasqualino [6 ]
机构
[1] Inst Anim Sci, Prague, Czech Republic
[2] Univ Warwick, Clin Sci Res Inst, Warwick, England
[3] Univ Bologna, Bologna, Italy
[4] Lab Tecnol Riprod, Cremona, Italy
[5] Ctr Cell Therapy & Tissue Repair, Libechov, Czech Republic
[6] Univ Teramo, Teramo, Italy
基金
英国医学研究理事会;
关键词
D O I
10.1016/j.tibtech.2008.06.001
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 [微生物学]; 0836 [生物工程]; 090102 [作物遗传育种]; 100705 [微生物与生化药学];
摘要
The recent vote in the British Parliament allows scientists in principle to create hybrid embryos by transferring human somatic cell nuclei into animal oocytes. This vote opens a fascinating new area of research with the central aim of generating interspecific lines of embryonic stem cells (ESCs) that could potentially be used to understand development, differentiation, gene expression and genomic compatibility. It will also promote human cell therapies, as well as the pharmaceutical industry's search for new drug targets. If this approach is to be successful, many biological questions need to be answered and, in addition, some moral and ethical aspects must be taken into account.
引用
收藏
页码:469 / 474
页数:6
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