Antigen-presenting cells and anti-Salmonella immunity

被引：30

作者：

Yrlid, U ^{[1
]}

Svensson, M ^{[1
]}

Kirby, A ^{[1
]}

Wick, MJ ^{[1
]}

机构：

[1] Lund Univ, Immunol Sect, Dept Cell & Mol Biol, S-22184 Lund, Sweden

来源：

MICROBES AND INFECTION | 2001年 / 3卷 / 14-15期

关键词：

Salmonella typhimurium; dendritic cell; macrophage; apoptosis; antigen presentation;

D O I：

10.1016/S1286-4579(01)01484-8

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The present article summarizes studies aimed at addressing the role of antigen-presenting cell populations, particularly dendritic cells (DC), in the immune response to Salmonella typhimurium, Data from in vitro studies shed light on presentation of antigens expressed in Salmonella on major histocompatibility complex class I and class II molecules by infected DC and macrophages, and the activation state of DC following infection. Finally, data from in vivo studies addressing the role of DC and defined DC subsets during the host response to Salmonella using a murine infection model are discussed. (C) 2001 Editions scientifiques et medicales Elsevier SAS.

引用

页码：1239 / 1248

页数：10