Bioactive peptides from marine sources: pharmacological properties and isolation procedures

被引:223
作者
Aneiros, A [1 ]
Garateix, A [1 ]
机构
[1] Minist Sci Technol & Environm, Ctr Marine Bioact Substances, Havana, Cuba
来源
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES | 2004年 / 803卷 / 01期
关键词
reviews; isolation; marine sources; peptides; bioactive;
D O I
10.1016/j.jchromb.2003.11.005
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Marine organisms represent a valuable source of new compounds. The biodiversity of the marine environment and the associated chemical diversity constitute a practically unlimited resource of new active substances in the field of the development of bioactive products. In this paper, the molecular diversity of different marine peptides is described as well as information about their biological properties and mechanisms of action is provided. Moreover, a short review about isolation procedures of selected bioactive marine peptides is offered. Novel peptides from sponges, ascidians, mollusks, sea anemones and seaweeds are presented in association with their pharmacological properties and obtainment methods. (C) 2003 Elsevier B.V. All rights reserved.
引用
收藏
页码:41 / 53
页数:13
相关论文
共 156 条
[1]  
ALSEN C, 1983, FED PROC, V42, P101
[2]  
ALVAREZ C, 2003, IN PRESS COMMENTS TO, V9, P1
[3]   Cloning, sequencing, and expression of equinatoxin .2. [J].
Anderluh, G ;
Pungercar, J ;
Strukelj, B ;
Macek, P ;
Gubensek, F .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1996, 220 (02) :437-442
[4]   Cytolytic peptide and protein toxins from sea anemones (Anthozoa: Actiniaria) [J].
Anderluh, G ;
Macek, P .
TOXICON, 2002, 40 (02) :111-124
[5]   A POTASSIUM CHANNEL TOXIN FROM THE SECRETION OF THE SEA-ANEMONE BUNODOSOMA-GRANULIFERA - ISOLATION, AMINO-ACID-SEQUENCE AND BIOLOGICAL-ACTIVITY [J].
ANEIROS, A ;
GARCIA, I ;
MARTINEZ, JR ;
HARVEY, AL ;
ANDERSON, AJ ;
MARSHALL, DL ;
ENGSTROM, A ;
HELLMAN, U ;
KARLSSON, E .
BIOCHIMICA ET BIOPHYSICA ACTA, 1993, 1157 (01) :86-92
[6]  
[Anonymous], 1997, Sci. Med. 1
[7]   THE NMR SOLUTION STRUCTURE OF A KUNITZ-TYPE PROTEINASE-INHIBITOR FROM THE SEA-ANEMONE STICHODACTYLA-HELIANTHUS [J].
ANTUCH, W ;
BERNDT, KD ;
CHAVEZ, MA ;
DELFIN, J ;
WUTHRICH, K .
EUROPEAN JOURNAL OF BIOCHEMISTRY, 1993, 212 (03) :675-684
[8]  
APT KE, 1995, PHOTOSYNTH RES, V135, P235
[9]   α-Conotoxins [J].
Arias, HR ;
Blanton, MP .
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 2000, 32 (10) :1017-1028
[10]  
BADAKERE S, 1982, TRENDS IMMUNOHAEMATO, V12, P101