Reductive lithiation of arylalkyl methyl ethers

被引：21

作者：

Azzena, U

Carta, S

Melloni, G

Sechi, A

机构：

[1] Dipartimento di Chimica, Università di Sassari, I-07100 Sassari

来源：

TETRAHEDRON | 1997年 / 53卷 / 47期

关键词：

D O I：

10.1016/S0040-4020(97)10080-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We have investigated the reductive cleavage of arylalkyl methyl ethers with an excess of lithium metal and a catalytic amount of naphthalene. The reaction proceeds regioselectively in the presence of various substituents on the aromatic ring, allowing access to a wide array of arylalkyl lithium derivatives, some of which are not easily accessible by conventional methods. (C) 1997 Elsevier Science Ltd.

引用

页码：16205 / 16212

页数：8

共 17 条

[1] Simple synthesis of 5-substituted resorcinols: A revisited family of interesting bioactive molecules [J].