Neck muscle responses to stimulation of monkey superior colliculus. II. Gaze shift initiation and volitional head movements

被引:76
作者
Corneil, BD
Olivier, E
Munoz, DP [1 ]
机构
[1] Queens Univ, Dept Physiol, Canadian Inst Hlth, Res Grp Sensory Motor Syst,Ctr Neurosci Studies, Kingston, ON K7L 3N6, Canada
[2] Univ Louvain, Sch Med, Neurophysiol Lab, B-1200 Brussels, Belgium
关键词
D O I
10.1152/jn.2002.88.4.2000
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
We report neck muscle activity and head movements evoked by electrical stimulation of the superior colliculus (SC) in head-unrestrained monkeys. Recording neck electromyography (EMG) circumvents complications arising from the head's inertia and the kinetics of muscle force generation and allows precise assessment of the neuromuscular drive to the head plant. This study served two main purposes. First, we sought to test the predictions made in the companion paper of a parallel drive from the SC onto neck muscles. Low-current, long-duration stimulation evoked both neck EMG responses and head movements either without or prior to gaze shifts, testifying to a SC drive to neck muscles that is independent of gaze-shift initiation. However, gaze-shift initiation was linked to a transient additional EMG response and head acceleration, confirming the presence of a SC drive to neck muscles that is dependent on gaze-shift initiation. We forward a conceptual neural architecture and suggest that this parallel drive provides the oculomotor system with the flexibility to orient the eyes and head independently or together, depending on the behavioral context. Second, we compared the EMG responses evoked by SC stimulation to those that accompanied volitional head movements. We found characteristic features in the underlying pattern of evoked neck EMG that were not observed during volitional head movements in spite of the seemingly natural kinematics of evoked head movements. These features included reciprocal patterning of EMG activity on the agonist and antagonist muscles during stimulation, a poststimulation increase in the activity of antagonist muscles, and synchronously evoked responses on agonist and antagonist muscles regardless of initial horizontal head position. These results demonstrate that the electrically evoked SC drive to the head cannot be considered as a neural replicate of the SC drive during volitional head movements and place important new constraints on the interpretation of electrically evoked head movements.
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页码:2000 / 2018
页数:19
相关论文
共 106 条
[51]  
IWAMOTO Y, 1990, EXP BRAIN RES, V80, P277
[52]   Evidence against direct connections to PPRF EBNs from SC in the monkey [J].
Keller, EL ;
McPeek, RM ;
Salz, T .
JOURNAL OF NEUROPHYSIOLOGY, 2000, 84 (03) :1303-1313
[53]  
KELLER EL, 1981, PROGR OCULOMOTOR RES, P57
[54]   BYPASSING THE SACCADIC PULSE-GENERATOR - POSSIBLE CONTROL OF HEAD MOVEMENT TRAJECTORY BY RAT SUPERIOR COLLICULUS [J].
KING, SM ;
DEAN, P ;
REDGRAVE, P .
EUROPEAN JOURNAL OF NEUROSCIENCE, 1991, 3 (08) :790-801
[55]   The superior colliculus encodes gaze commands in retinal coordinates [J].
Klier, EM ;
Wang, HY ;
Crawford, JD .
NATURE NEUROSCIENCE, 2001, 4 (06) :627-632
[56]   THE VESTIBULOOCULAR REFLEX DURING HUMAN SACCADIC EYE-MOVEMENTS [J].
LAURUTIS, VP ;
ROBINSON, DA .
JOURNAL OF PHYSIOLOGY-LONDON, 1986, 373 :209-233
[57]  
LESTIENNE F, 1984, EXP BRAIN RES, V53, P349
[58]   Apparent dissociation between saccadic eye movements and the firing patterns of premotor neurons and motoneurons [J].
Ling, L ;
Fuchs, AF ;
Phillips, JO ;
Freedman, EG .
JOURNAL OF NEUROPHYSIOLOGY, 1999, 82 (05) :2808-2811
[59]  
Loeb GE, 1986, ELECTROMYOGRAPHY EXP
[60]  
MASINO T, 1993, J NEUROSCI, V13, P351