Secondary Electrospray Ionization (SESI) of Ambient Vapors for Explosive Detection at Concentrations Below Parts Per Trillion

被引：114

作者：

Martinez-Lozano, Pablo ^{[1
,2
]}

Rus, Juan ^{[2
]}

Fernandez de la Mora, Gonzalo ^{[2
]}

Hernandez, Marta ^{[3
]}

Fernandez de la Mora, Juan ^{[1
]}

机构：

[1] Yale Univ, Dept Mech Engn, New Haven, CT 06520 USA

[2] SEADM, Valladolid, Spain

[3] CARTIF, Valladolid, Spain

来源：

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY | 2009年 / 20卷 / 02期

关键词：

FLIGHT MASS-SPECTROMETRY; MS; CONTRABAND; BREATH;

D O I：

10.1016/j.jasms.2008.10.006

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We determine the sensitivity of several commercial atmospheric pressure ionization mass spectrometers towards ambient vapors, ionized by contact with an electrospray of acidified or ammoniated solvent, a technique often referred to as secondary electrospray ionization (SESI). Although a record limit of detection of 0.2 X 10(12) atmospheres (0.2 ppt) is found for explosives such as PETN and 0.4 ppt for TNT (without preconcentration), this still implies the need for some 10(8)-10(9) vapor molecules/s for positive identification of explosives. This extremely inefficient use of sample is partly due to low charging probability (similar to 10(4)), finite ion transmission, and Counting probability in the mass spectrometer (1/10 in quadrupoles), and a variable combination of duty cycle and background noise responsible typically for a 10(3) factor loss of useful signal. (J Am Soc Mass Spectrom 2009, 20, 287-294) 0 2009 Published by Elsevier Inc. on behalf of American Society for Mass Spectrometry

引用

页码：287 / 294

页数：8

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