PARALLEL MONITORING FOR MULTIPLE TARGETED COMPOUNDS BY ION-TRAP MASS-SPECTROMETRY

被引：28

作者：

ASANO, KG ^{[1
]}

GOERINGER, DE ^{[1
]}

MCLUCKEY, SA ^{[1
]}

机构：

[1] OAK RIDGE NATL LAB,DIV CHEM & ANALYT SCI,OAK RIDGE,TN 37831

来源：

ANALYTICAL CHEMISTRY | 1995年 / 67卷 / 17期

关键词：

D O I：

10.1021/ac00113a003

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

An approach to monitoring for the presence of several targeted compounds simultaneously using ion trap mass spectrometry is described. The use of tailored waveforms sequentially applied to the ion trap end-cap electrodes allows for mass-selective accumulation of multiple parent ions and simultaneous collisional activation of the ions. Further mass selection and ion activation steps can be performed to enhance specificity, The detection of trace explosives in air is used as an illustrative case in which 2,4-dinitrotoluene, 2,4,6-trinitrotoluene, and (2,4,6-trinitrophenyl)methylnitramine are targeted for detection. The parallel monitoring scheme trades specificity for advantages in speed and duty cycle relative to tandem mass spectrometry experiments performed in series.

引用

页码：2739 / 2742

页数：4

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