Skipping into the E2F1-destruction pathway

被引:29
作者
Harper, JW [1 ]
Elledge, SJ
机构
[1] Baylor Coll Med, Verna & Marrs McLean Dept Biochem, Houston, TX 77030 USA
[2] Baylor Coll Med, Howard Hughes Med Inst, Houston, TX 77030 USA
[3] Baylor Coll Med, Dept Biochem, Houston, TX 77030 USA
关键词
D O I
10.1038/8952
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
F-box proteins act as specificity factors for the ubiquitination, and thus degradation, of target proteins. New results point to the importance of F-box proteins in controlling the transcriptional programs that regulate development and the cell cycle.
引用
收藏
页码:E5 / E7
页数:3
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