'Natural' light treatment of seasonal affective disorder

被引:112
作者
WirzJustice, A [1 ]
Graw, P [1 ]
Krauchi, K [1 ]
Sarrafzadeh, A [1 ]
English, J [1 ]
Arendt, J [1 ]
Sand, L [1 ]
机构
[1] UNIV SURREY, DEPT BIOL SCI, GUILDFORD GU2 5XH, SURREY, ENGLAND
关键词
seasonal affective disorder; placebo tight therapy; natural light exposure; salivary melatonin; cortisol;
D O I
10.1016/0165-0327(95)00081-X
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Patients with seasonal affective disorder (SAD) were treated for 1 week either with a daily 1-h morning walk outdoors (natural light) or low-dose artificial light (0.5 h @ 2800 lux). The latter treatment (given under double-blind conditions) can be considered mainly placebo and did not improve any of the depression self-ratings, whereas natural light exposure improved all self-ratings. According to the Hamilton depression score, 25% remitted after low-dose artificial light and 50% after the walk. Sleep duration or timing were not crucial for the therapeutic response. The morning walk phase-advanced the onset and/or offset of salivary melatonin secretion, but individual clinical improvement could not be correlated with specific phase-shifts. Morning cortisol was decreased. Low-dose artificial light did not modify melatonin or cortisol patterns. This is the first study to provide evidence for the use of outdoor light exposure as a potential alternative or adjuvant to conventional artificial light therapy in SAD.
引用
收藏
页码:109 / 120
页数:12
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