Isolation and identification of a new bifidogenic growth stimulator produced by Propionibacterium freudenreichii ET-3

被引：75

作者：

Isawa, K ^{[1
]}

Hojo, K ^{[1
]}

Yoda, N ^{[1
]}

Kamiyama, T ^{[1
]}

Makino, S ^{[1
]}

Saito, M ^{[1
]}

Sugano, H ^{[1
]}

Mizoguchi, C ^{[1
]}

Kurama, S ^{[1
]}

Shibasaki, M ^{[1
]}

Endo, N ^{[1
]}

Sato, Y ^{[1
]}

机构：

[1] Meiji Dairies Corp, Food Funct Res Inst, Kanagawa 2500862, Japan

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2002年 / 66卷 / 03期

关键词：

1,4-dihydroxy-2-naphthoic acid; bifidogenic growth stimulator; Propionibacterium freudenreichii;

D O I：

10.1271/bbb.66.679

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We have found a new growth stimulator for bifidobacteria in the culture broth of Propionibacterium freudenrelchii ET-3. The bifidogenic growth stimulator (BGS) was purified by Diaion HP-20 column chromatography and preparative HPLC. Spectroscopic methods including H-1-NMR, UV, and LC-ESI-MS experiments indicated that the chemical structure of the bifidogenic growth stimulator was 1,4-dihydroxy-2-naphthoic acid (DHNA). Approximately 10 mg/L of DHNA was found to be produced in the culture broth of P. freudenreichii ET-3.

引用

页码：679 / 681

页数：3

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