Adesmia aegiceras:: antimicrobial activity and chemical study

被引:45
作者
Agnese, AM
Pérez, C
Cabrera, JL
机构
[1] Univ Nacl Cordoba, Fac Ciencias Quim, Dept Farm, IMBIV,CONICET, RA-5000 Cordoba, Argentina
[2] Univ Buenos Aires, Fac Odontol, Catedra Farmacol, Buenos Aires, DF, Argentina
关键词
Adesmia aegiceras; Fabaceae; antimicrobial activity; chemical components;
D O I
10.1078/0944-7113-00059
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
The antimicrobial activity of the ethanolic extract of Adesmia aegiceras was studied by the agar-well diffusion method. Antibacterial activity against Micrococcus luteus and eight pathogenic bacterial strains as well as antifungal activity against Candida albicans, was detected. Bacterial and fungal strains exhibited similar concentration-response curves (EC50 and R-max values) and similar MIC. The MBC/MIC was about 8. These data would indicate the potential usefulness of the A. aegiceras extract as a microbiostatic, antiseptic or disinfectant agent. Furthermore, chemical study of the bioactive alcoholic extract was performed, which revealed quercetin, isorhamnetin-3-rutinoside, isovitexin, pinitol and chlorogenic acid as its main components.
引用
收藏
页码:389 / 394
页数:6
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