An efficient synthesis of polysubstituted pyrroles via copper-catalyzed coupling of oxime acetates with dialkyl acetylenedicarboxylates under aerobic conditions

被引：124

作者：

Tang, Xiaodong ^{[1
]}

Huang, Liangbin ^{[1
]}

Qi, Chaorong ^{[1
]}

Wu, Wanqing ^{[1
]}

Jiang, Huanfeng ^{[1
]}

机构：

[1] S China Univ Technol, Sch Chem & Chem Engn, Guangzhou 510640, Guangdong, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2013年 / 49卷 / 83期

基金：

中国国家自然科学基金; 中国博士后科学基金;

关键词：

H BOND FUNCTIONALIZATION; REGIOSELECTIVE SYNTHESIS; ONE-POT; SUBSTITUTED PYRROLES; SEQUENTIAL REACTIONS; CYCLOADDITION; ANNULATION; RUTHENIUM; ALKYNES; FURANS;

D O I：

10.1039/c3cc44896g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A Cu-catalyzed [3+2]-type condensation reaction of oxime acetates and dialkyl acetylenedicarboxylates that provides highly substituted pyrroles under aerobic conditions is described. The newly formed pyrroles are easily employed for further transformations to prepare pyrrolo[2,1-a]isoquinoline skeletons.

引用

页码：9597 / 9599

页数：3

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