Copper-Catalyzed Tandem Reactions of 1-(2-Iodoary)-2-yn-1-ones with Isocyanides for the Synthesis of 4-Oxo-indeno[1,2-b]pyrroles

被引：87

作者：

Cai, Qian ^{[1
]}

Zhou, Fengtao

Xu, Tianfeng

Fu, Liangbing

Ding, Ke

机构：

[1] Chinese Acad Sci, Guangzhou Inst Biomed & Hlth, Key Lab Regenerat Biol, Guangzhou 510530, Guangdong, Peoples R China

来源：

ORGANIC LETTERS | 2011年 / 13卷 / 02期

关键词：

ALPHA-METALATED ISOCYANIDES; ASYMMETRIC ALDOL REACTION; COUPLING REACTIONS; OLIGOSUBSTITUTED PYRROLES; CROSS-CYCLOADDITION; CARBONYL-COMPOUNDS; ISOCYANOACETATE; ALDEHYDES; COMPLEX; DERIVATIVES;

D O I：

10.1021/ol102826f

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel copper-catalyzed tandem reaction of 1-(2-iodoaryl)-2-yn-1-ones with isocyanides is described. The reaction is through a formal [3 + 2] cycloaddition/coupling tandem process and leads to efficient formation of 4-oxo-indeno[1,2-b]pyrroles.

引用

页码：340 / 343

页数：4

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