Whole-brain radiotherapy in the management of brain metastasis

被引:354
作者
Khuntia, D
Brown, P
Li, J
Mehta, MP
机构
[1] Univ Wisconsin, Dept Human Oncol, Madison, WI 53792 USA
[2] Mayo Clin, Rochester, MN USA
关键词
D O I
10.1200/JCO.2005.04.6185
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Brain metastases are an important cause of morbidity and mortality, afflicting nearly 170,000 Americans annually. The prognosis for these patients is poor, with median survival times measured in months. In this review article, we present the standard treatment approach of whole-brain radiotherapy and discuss new directions, including the role of chemical modifiers and the management and prevention of neurocognitive deficits.
引用
收藏
页码:1295 / 1304
页数:10
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