Nuclear hormone receptors in T lymphocytes

被引:212
作者
Winoto, A
Littman, DR
机构
[1] NYU, Sch Med, Skirball Inst Biomol Med, Howard Hughes Med Inst, New York, NY 10016 USA
[2] Univ Calif Berkeley, Dept Mol & Cell Biol, LSA 469, Berkeley, CA 94720 USA
关键词
D O I
10.1016/S0092-8674(02)00710-9
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Among the numerous steroid and orphan nuclear receptors encoded within mammalian genomes, several are involved in regulating immune system functions. We review here recent studies on the glucocorticoid receptor and the orphan receptors Nur77 and RORgamma. These molecules play key roles in the development and the effector functions of T lymphocytes.
引用
收藏
页码:S57 / S66
页数:10
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