Transferable cefoxitin resistance in enterobacteria from Greek hospitals and characterization of a plasmid-mediated group 1 beta-lactamase (LAT-2)

被引:63
作者
Gazouli, M [1 ]
Tzouvelekis, LS [1 ]
Prinarakis, E [1 ]
Miriagou, V [1 ]
Tzelepi, E [1 ]
机构
[1] HELLENIC PASTEUR INST, DEPT BACTERIOL, GR-11521 ATHENS, GREECE
关键词
D O I
10.1128/AAC.40.7.1736
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Cefoxitin resistance in Klebsiella pneumoniae and Escherichia coli strains isolated in Greek hospitals was found to be due to the acquisition of similar plasmids coding for group 1 beta-lactamases. The plasmids were not self-transferable but were mobilized by conjugative plasmids. These elements have also been spread to Enterobacter aerogenes, The most common enzyme was a Citrobacter freundii-derived cephalosporinase (LAT-2) which differed from LAT-1 by three amino acids.
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页码:1736 / 1740
页数:5
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