Pneumococcal pneumonia and influenza: A deadly combination

被引：106

作者：

Klugman, Keith P. ^{[1
,2
]}

Chien, Yu-Wen ^{[1
]}

Madhi, Shabir A. ^{[2
,3
]}

机构：

[1] Emory Univ, Rollins Sch Publ Hlth, Atlanta, GA 30322 USA

[2] Univ Witwatersrand, Resp & Meningeal Pathogens Res Unit, MRC, Johannesburg, South Africa

[3] Univ Witwatersrand, Dept Sci & Technol, Natl Res Fdn Vaccine Preventable Dis, Johannesburg, South Africa

来源：

VACCINE | 2009年 / 27卷

关键词：

Pneumococcal pneumonia; Influenza; PCV7; COMMUNITY-ACQUIRED PNEUMONIA; CONJUGATE VACCINE EFFICACY; C-REACTIVE PROTEIN; STREPTOCOCCUS-PNEUMONIAE; PANDEMIC INFLUENZA; STANDARDIZED INTERPRETATION; HOSPITALIZED CHILDREN; RESPIRATORY-INFECTION; BACTERIAL PNEUMONIA; CHEST RADIOGRAPHS;

D O I：

10.1016/j.vaccine.2009.06.007

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Significant morbidity due to pneumococcal co-infection is associated with viral respiratory infections. Pneumonia is the leading cause of death in children worldwide. The incidence of clinical pneumonia among children in the United States decreased 39% following the introduction of a seven-valent pneumococcal conjugate vaccine (PCV). PCVs have also reduced hospitalisations associated with influenza in children. The majority of the mortality associated with the influenza pandemic of 1918 was attributable to bacterial infections, especially the pneumococcus. Vaccination with PCV for children and pneumococcal polysaccharide vaccine for adults should be considered essential to pandemic influenza preparedness. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：C9 / C14

页数：6

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