1-[2'-(trimethylsilyl)ethoxymethyl]-2-phenylsulfonylimidazole: A new reagent for the preparation of C-4 substituted imidazoles

被引：10

作者：

Phillips, JG ^{[1
]}

Fadnis, L ^{[1
]}

Williams, DR ^{[1
]}

机构：

[1] INDIANA UNIV,DEPT CHEM,BLOOMINGTON,IN 47405

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 45期

关键词：

D O I：

10.1016/S0040-4039(97)10128-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The title compound provides for the efficient C-4 metallation of the imidazole nucleus. Further reactions lead to trisubstituted imidazoles which can be selectively deprotected at the N-1 and C-2 positions under mild conditions to maximize the potential for further elaboration. (C) 1997 Elsevier Science Ltd.

引用

页码：7835 / 7838

页数：4

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