Phosphoproteomics: Unraveling the signaling web

被引：47

作者：

Huang, Paul H. ^{[1
]}

White, Forest M. ^{[1
,2
]}

机构：

[1] MIT, Dept Biol Engn, Cambridge, MA 02139 USA

[2] MIT, Koch Inst Integrat Canc Res, Cambridge, MA 02139 USA

来源：

MOLECULAR CELL | 2008年 / 31卷 / 06期

关键词：

D O I：

10.1016/j.molcel.2008.09.001

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In recent years, phosphoproteomic technologies have increased our understanding of cellular signaling networks. Here, we frame recent phosphoproteomics-based advances in the context of the DNA damage response and ErbB receptor family signaling and offer a perspective on how the molecular insights arising from the integration of such proteomic approaches might be used for clinical applications.

引用

收藏

页码：777 / 781

页数：5

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