AngioDB: database of angiogenesis and angiogenesis-related molecules

被引:4
作者
Sohn, TK
Moon, EJ
Lee, SK
Cho, HG
Kim, KW [1 ]
机构
[1] Seoul Natl Univ, Pharmaceut Sci Res Inst, Angiogenesis Res Lab, Seoul 151742, South Korea
[2] Pusan Natl Univ, Grad Program Bioinformat, Pusan 609735, South Korea
[3] Pusan Natl Univ, Dept Mol Biol, Pusan 609735, South Korea
[4] Pusan Natl Univ, Dept Comp Sci, Graph Applicat Lab, Pusan 609735, South Korea
[5] Seoul Natl Univ, Coll Pharm, Seoul 151742, South Korea
关键词
D O I
10.1093/nar/30.1.369
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Angiogenesis is the formation of new capillaries sprouting from pre-existing vessels. Angiogenesis occurs in a variety of normal physiological and pathological conditions and is regulated by a balance of stimulatory and inhibitory angiogenic factors. The control of this balance may fail and result in the formation of a pathologic capillary network during the development of many diseases. Therefore, we developed the angiogenesis database (AngioDB), which can provide a signaling network of angiogenesis-related biomolecules in human. Each record of AngioDB consisted of 12 fields and was developed by using a relational database management system. For the retrieval of data, Active Server Page (ASP) technology was integrated in this system. Users can access the database by a query or imagemap browsing program. The retrieving system also provides a list of angiogenesis-related molecules classified by three categories, and the database has an external link to NCBI databases. AngioDB is available via the Internet at http://angiodb.snu.ac.kr/.
引用
收藏
页码:369 / 371
页数:3
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