Calcium and vitamin D in the prevention and treatment of osteoporosis - a clinical update

被引：86

作者：

Boonen, S.

Vanderschueren, D.

Haentjens, P.

Lips, P.

机构：

[1] Leuven Univ, Ctr Metab Bone Dis, B-3000 Louvain, Belgium

[2] Katholieke Univ Leuven, Div Geriatr Med, Louvain, Belgium

[3] Katholieke Univ Leuven, Div Endocrinol, Louvain, Belgium

[4] Vrije Univ Brussel, Dept Orthopaed & Traumatol, Brussels, Belgium

[5] Vrije Univ Amsterdam Med Ctr, Dept Endocrinol, Amsterdam, Netherlands

来源：

JOURNAL OF INTERNAL MEDICINE | 2006年 / 259卷 / 06期

关键词：

calcium; osteoporosis; vitamin D;

D O I：

10.1111/j.1365-2796.2006.01655.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Combined calcium and vitamin D supplementation is an essential component of the management of osteoporosis, supported by a strong scientific rationale. The types of individuals who should receive calcium and vitamin D supplements are those: (i) patients with documented osteoporosis receiving antiresorptive or anabolic treatment; (ii) patients receiving glucocorticoids; and (iii) individuals with or at high risk of calcium and/or vitamin D insufficiencies, in particular older women and men. This article describes the evidence base that supports targeting these groups. Benefits are most apparent when 800 IU day(-1) vitamin D is complemented with a dose of 1000-1200 mg day(-1) elemental calcium. Compliance is also key to optimizing clinical efficacy.

引用

收藏

页码：539 / 552

页数：14

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