Bone status assessed by quantitative ultrasound in children with inflammatory bowel disease: a comparison with DXA

被引：9

作者：

Bak-Drabik, Katarzyna ^{[1
]}

Adamczyk, Piotr ^{[1
]}

Chobot, Agata ^{[2
]}

Kwiecien, Jaroslaw ^{[1
]}

Pluskiewicz, Wojciech ^{[3
]}

机构：

[1] Med Univ Silesia, Sch Med, Dept Pediat, Div Dent Zabrze, Katowice, Poland

[2] Publ Clin Hosp 1, Dept Pediat, Zabrze, Poland

[3] Med Univ Silesia, Sch Med, Dept Internal Med Diabetol & Nephrol, Div Dent Zabrze,Metab Bone Dis Unit, Katowice, Poland

来源：

EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY | 2016年 / 10卷 / 11期

关键词：

Inflammatory bowel diseases; bone mineral status; quantitative ultrasound; X-RAY ABSORPTIOMETRY; STAGE RENAL-FAILURE; MINERAL DENSITY; SKELETAL STATUS; PEDIATRIC-PATIENTS; YOUNG-ADULTS; OSTEOPOROSIS; ADOLESCENTS; GROWTH; MASS;

D O I：

10.1080/17474124.2016.1242410

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

100201 [内科学];

摘要：

Background: To determine the bone status in children with inflammatory bowel diseases (IBD) using quantitative ultrasound (QUS) measurement at hand phalanges and compare the obtained results with dual-energy X-ray absorptiometry (DXA).Methods: Fifty-one children with IBD underwent DXA and QUS measurements at hand phalanges in the year 2013. The control group for the QUS consisted of 460 children. Reference data for DXA comes from Hologic Explorer.Results: QUS measurements did not differ significantly between IBD patients and healthy controls. There was no difference between UC and CD subjects. DXA measurements in patients with IBD were lower than in the healthy population. Tanner stage and nutritional status correlated with bone status contrary to steroids therapy.Conclusion: Low bone mineral density often complicates IBD in children. QUS is not an appropriate method for the assessment of bone status in children. Nutritional status seems to have a greater impact on bone status than corticosteroids therapy.

引用

页码：1305 / 1312

页数：8

共 38 条

[1]

Bone mineral assessment by dual energy X-ray Absorptiometry in children with inflammatory bowel disease: Evaluation by age or bone area [J].

Ahmed, SF ;

Horrocks, IA ;

Patterson, T ;

Zaidi, S ;

Ling, TC ;

McGrogan, T ;

Weaver, TT .

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 2004, 38 (03) :276-280

[2]

Albrecht P, 2014, GASTROENTEROLOGIA PR, P25

[3]

Quantitative ultrasound methods to assess bone mineral status in children: Technical characteristics, performance, and clinical application [J].

Baroncelli, Giampiero I. .

PEDIATRIC RESEARCH, 2008, 63 (03) :220-228

[4]

Review article: Osteoporosis and inflammatory bowel disease [J].

Bernstein, CN ;

Leslie, WD .

ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 2004, 19 (09) :941-952

[5]

Evaluation of the usefulness of a quantitative ultrasound device in screening of bone mineral density in children [J].

Brukx, LJCE ;

Waelkens, JJJ .

ANNALS OF HUMAN BIOLOGY, 2003, 30 (03) :304-315

[6]

Whole body BMC in pediatric Crohn disease: Independent effects of altered growth, maturation, and body composition [J].

Burnham, JM ;

Shults, J ;

Semeao, E ;

Foster, B ;

Zemel, BS ;

Stallings, VA ;

Leonard, MB .

JOURNAL OF BONE AND MINERAL RESEARCH, 2004, 19 (12) :1961-1968

[7]

QUANTITATIVE ULTRASOUND BONE MEASUREMENTS IN PRE-PUBERTAL CHILDREN WITH TYPE 1 DIABETES [J].

Chobot, Agata P. ;

Haffke, Anna ;

Polanska, Joanna ;

Halaba, Zenon P. ;

Deja, Grazyna ;

Jarosz-Chobot, Przemyslawa ;

Pluskiewicz, Wojciech .

ULTRASOUND IN MEDICINE AND BIOLOGY, 2012, 38 (07) :1109-1115

[8]

Corticosteroid-induced osteoporosis: Does it occur in patients with Crohn's disease? [J].

de Jong, DJ ;

Corstens, FHM ;

Mannaerts, L ;

van Rossum, LGM ;

Naber, AHJ .

AMERICAN JOURNAL OF GASTROENTEROLOGY, 2002, 97 (08) :2011-2015

[9]

Obesity in Inflammatory Bowel Disease: A Marker of Less Severe Disease [J].

Flores, Avegail ;

Burstein, Ezra ;

Cipher, Daisha J. ;

Feagins, Linda A. .

DIGESTIVE DISEASES AND SCIENCES, 2015, 60 (08) :2436-2445

[10]

Bone mineral density assessment in children with inflammatory bowel disease [J].

Gokhale, R ;

Favus, MJ ;

Karrison, T ;

Sutton, MM ;

Rich, B ;

Kirschner, BS .

GASTROENTEROLOGY, 1998, 114 (05) :902-911

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