Novel Targeted Agents and the Need to Refine Clinical End Points in Chronic Lymphocytic Leukemia

被引：161

作者：

Cheson, Bruce D. ^{[1
]}

Byrd, John C. ^{[2
]}

Rai, Kanti R. ^{[3
]}

Kay, Neil E. ^{[4
]}

O'Brien, Susan M. ^{[5
]}

Flinn, Ian W. ^{[6
]}

Wiestner, Adrian ^{[7
]}

Kipps, Thomas J. ^{[8
]}

机构：

[1] Georgetown Univ Hosp, Lombardi Comprehens Canc Ctr, Washington, DC 20007 USA

[2] Ohio State Univ, Columbus, OH 43210 USA

[3] Long Isl Jewish Med Ctr, New Hyde Pk, NY 11042 USA

[4] Mayo Clin, Rochester, MN USA

[5] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA

[6] Sarah Cannon Res Inst, Nashville, TN USA

[7] NIH, Bethesda, MD 20892 USA

[8] Univ Calif San Diego, Moores Canc Ctr, San Diego, CA 92103 USA

来源：

JOURNAL OF CLINICAL ONCOLOGY | 2012年 / 30卷 / 23期

关键词：

B-CELL RECEPTOR; RESPONSE CRITERIA; CLL CELLS; LENALIDOMIDE; INHIBITOR; GUIDELINES; LYMPHOMA; DIAGNOSIS; CAL-101;

D O I：

10.1200/JCO.2012.43.3748

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：2820 / 2822

页数：3

共 20 条

[1] Phase II Study of Dasatinib in Relapsed or Refractory Chronic Lymphocytic Leukemia [J].

Amrein, Philip C. ;

Attar, Eyal C. ;

Takvorian, Tak ;

Hochberg, Ephraim P. ;

Ballen, Karen K. ;

Leahy, Kathleen M. ;

Fisher, David C. ;

LaCasce, Ann S. ;

Jacobsen, Eric D. ;

Armand, Philippe ;

Hasserjian, Robert P. ;

Werner, Lillian ;

Neuberg, Donna ;

Brown, Jennifer R. .

CLINICAL CANCER RESEARCH, 2011, 17 (09) :2977-2986

[2] Clinical efficacy of lenalidomide in patients with relapsed or refractory chronic lymphocytic leukemia: Results of a phase II study [J].

Chanan-Khan, Asher ;

Miller, Kena C. ;

Musial, Laurie ;

Lawrence, David ;

Padmanabhan, Swaminathan ;

Takeshita, Kenichi ;

Porter, Carl W. ;

Goodrich, David W. ;

Bernstein, Zale P. ;

Wallace, Paul ;

Spaner, David ;

Mohr, Alice ;

Byrne, Catriona ;

Hernandez-Ilizaliturri, Francisco ;

Chrystal, Cynthia ;

Starostik, Petr ;

Czuczman, Myron S. .

JOURNAL OF CLINICAL ONCOLOGY, 2006, 24 (34) :5343-5349

[3] Tumor Flare Reaction Associated With Lenalidomide Treatment in Patients With Chronic Lymphocytic Leukemia Predicts Clinical Response [J].

Chanan-Khan, Asher ;

Miller, Kena C. ;

Lawrence, David ;

Padmanabhan, Swaminathan ;

Miller, Austin ;

Hernandez-Illatazurri, Francisco ;

Czuczman, Myron S. ;

Wallace, Paul K. ;

Zeldis, Jerome B. ;

Lee, Kelvin .

CANCER, 2011, 117 (10) :2127-2135

[4] Biological effects and clinical significance of lenalidomide-induced tumour flare reaction in patients with chronic lymphocytic leukaemia: in vivo evidence of immune activation and antitumour response [J].

Chanan-Khan, Asher A. ;

Chitta, Kasyapa ;

Ersing, Noreen ;

Paulus, Aneel ;

Masood, Aisha ;

Sher, Taimur ;

Swaika, Abhisek ;

Wallace, Paul K. ;

Mashtare, Terry L., Jr. ;

Wilding, Greg ;

Lee, Kelvin ;

Czuczman, Myron S. ;

Borrello, Ivan ;

Bangia, Naveen .

BRITISH JOURNAL OF HAEMATOLOGY, 2011, 155 (04) :457-467

[5] GUIDELINES FOR CLINICAL PROTOCOLS FOR CHRONIC LYMPHOCYTIC-LEUKEMIA - RECOMMENDATIONS OF THE NATIONAL-CANCER-INSTITUTE-SPONSORED-WORKING-GROUP [J].

CHESON, BD ;

BENNETT, JM ;

RAI, KR ;

GREVER, MR ;

KAY, NE ;

SCHIFFER, CA ;

OKEN, MM ;

KEATING, MJ ;

BOLDT, DH ;

KEMPIN, SJ ;

FOON, KA .

AMERICAN JOURNAL OF HEMATOLOGY, 1988, 29 (03) :152-163

[6] National Cancer Institute-sponsored Working Group guidelines for chronic lymphocytic leukemia: Revised guidelines for diagnosis and treatment [J].

Cheson, BD ;

Bennett, JM ;

Grever, M ;

Kay, N ;

Keating, MJ ;

OBrien, S ;

Rai, KR .

BLOOD, 1996, 87 (12) :4990-4997

[7] Revised response criteria for malignant lymphoma [J].

Cheson, Bruce D. ;

Pfistner, Beate ;

Juweid, Malik E. ;

Gascoyne, Randy D. ;

Specht, Lena ;

Horning, Sandra J. ;

Coiffier, Bertrand ;

Fisher, Richard I. ;

Hagenbeek, Anton ;

Zucca, Emanuele ;

Rosen, Steven T. ;

Stroobants, Sigrid ;

Lister, T. Andrew ;

Hoppe, Richard T. ;

Dreyling, Martin ;

Tobinai, Kensei ;

Vose, Julie M. ;

Connors, Joseph M. ;

Federico, Massimo ;

Diehl, Volker .

JOURNAL OF CLINICAL ONCOLOGY, 2007, 25 (05) :579-586

[8]

Coutre SE, 2011, J CONTRACEPT FERTIL, V29, p451s

[9] Phase I/II study of galiximab, an Anti-CD80 antibody, for relapsed or refractory follicular lymphoma [J].

Czuczman, MS ;

Thall, A ;

Witzig, TE ;

Vose, JM ;

Younes, A ;

Emmanouilides, C ;

Miller, TP ;

Moore, JO ;

Leonard, JP ;

Gordon, LI ;

Sweetenham, J ;

Alkuzweny, B ;

Finucane, DM ;

Leigh, BR .

JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (19) :4390-4398

[10] The clinically active BTK inhibitor PCI-32765 targets B-cell receptor- and chemokine-controlled adhesion and migration in chronic lymphocytic leukemia [J].

de Rooij, Martin F. M. ;

Kuil, Annemieke ;

Geest, Christian R. ;

Eldering, Eric ;

Chang, Betty Y. ;

Buggy, Joseph J. ;

Pals, Steven T. ;

Spaargaren, Marcel .

BLOOD, 2012, 119 (11) :2590-2594

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