Metabolomics explained to perinatologists and pediatricians

被引：5

作者：

Atzori, Luigi ^{[1
]}

Barberini, Luigi ^{[2
]}

Santoru, Maria Laura ^{[1
]}

Antonucci, Roberto ^{[3
]}

Fanos, Vassilios ^{[4
]}

机构：

[1] Univ Cagliari, Dept Biomed Sci, Cagliari, Italy

[2] Univ Cagliari, Dept Publ Hlth Clin & Mol Med, Cagliari, Italy

[3] Nostra Signora Bonaria Hosp, Div Neonatol & Pediat, San Gavino Monreale, Italy

[4] Univ Cagliari, Dept Surg Sci, Neonatal Intens Care Unit, Cagliari, Italy

来源：

JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE | 2012年 / 25卷

关键词：

Metabolomics; neonatology; Omics; perinatology; pediatrics; MOUSE; TOOL;

D O I：

10.3109/14767058.2012.714636

中图分类号：

R71 [妇产科学];

学科分类号：

100211 [妇产科学];

摘要：

Metabolomics is a new approach based on the systematic study of the full complement of low-molecular weight compounds (e.g. sugars, lipids, hormones, vitamins, secondary metabolites), both endogenous and exogenous, found within a cell, tissue, biofluid or organism. In order to avoid false expectation by using a metabolomics approach, it is important to have: (i) a properly planned design of the study based on a clear question to be answered, (ii) an appropriate knowledge of the equipments available; (iii) a proper statistical analysis and support and (iv) a validation of the results obtained. In the present short-review, these topics will be briefly described.

引用

页码：10 / 12

页数：3

共 21 条

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