Genetic characterization of Mycobacterium avium isolates recovered from humans and animals in Australia

被引：24

作者：

Feizabadi, MM

Robertson, ID

Cousins, DV

Dawson, D

Chew, W

Gilbert, GL

Hampson, DJ

机构：

[1] MURDOCH UNIV,SCH VET STUDIES,MURDOCH,WA 6150,AUSTRALIA

[2] DEPT AGR,AUSTRALIAN REFERENCE LAB BOVINE TB,S PERTH,WA 6151,AUSTRALIA

[3] STATE HLTH LAB SERV,BRISBANE,QLD 4000,AUSTRALIA

[4] WESTMEAD HOSP,MYCOBACTERIUM REFERENCE LAB,SYDNEY,NSW 2145,AUSTRALIA

来源：

EPIDEMIOLOGY AND INFECTION | 1996年 / 116卷 / 01期

关键词：

D O I：

10.1017/S0950268800058945

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Genetic relationships amongst 115 mainly Australian isolates of Mycobacterium avium were assessed using multilocus enzyme electrophoresis (MEE). The isolates were divided into 58 electrophoretic types (ETs), with a mean genetic diversity of 0.29. Isolates from humans were closely related to but distinct from those cultured from birds, whilst some porcine isolates belonged to the same ETs as certain human isolates. Pulsed held gel electrophoresis (PFGE) was used to differentiate related isolates, and those from birds and some from other animals, including pigs, were distinguished from the human isolates. The results of MEE and PFGE suggested that certain strains of M. avium may be transmitted between birds and pigs, but there was no clear evidence of transmission to humans. The serovar of the M. avium isolates was not obviously related to their ET assignment or their PFGE type.

引用

页码：41 / 49

页数：9

共 44 条

[41] SEROVAR DETERMINATION AND MOLECULAR TAXONOMIC CORRELATION IN MYCOBACTERIUM-AVIUM, MYCOBACTERIUM-INTRACELLULARE, AND MYCOBACTERIUM-SCROFULACEUM - A COOPERATIVE STUDY OF THE INTERNATIONAL WORKING GROUP ON MYCOBACTERIAL TAXONOMY [J].