Control of metalloprotein redox potentials: What does site-directed mutagenesis of hemoproteins tell us?

被引：112

作者：

Mauk, AG

Moore, GR

机构：

[1] UNIV E ANGLIA,SCH CHEM SCI,CTR METALLOPROT SPECT & BIOL,NORWICH NR4 7TJ,NORFOLK,ENGLAND

[2] UNIV BRITISH COLUMBIA,DEPT BIOCHEM,VANCOUVER,BC V6T 1W5,CANADA

来源：

JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY | 1997年 / 2卷 / 01期

关键词：

redox potentials; hemoproteins; electrostatic interactions;

D O I：

10.1007/s007750050115

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

An overview of factors affecting metalloprotein redox potentials is given, together with an assessment of the role of site-directed mutagenesis of hemoproteins in investigating this topic and a description of several theoretically challenging hemoproteins. The conclusion is reached that a quantitative and experimentally testable description of metalloprotein redox potentials is not yet available.

引用

页码：119 / 125

页数：7

共 51 条

[1] ARMSTRONG RA, 1997, JBIC 2 8 NNN
[2] Individual reduction potentials of the iron ions in Fe2S2 and high-potential Fe4S4 ferredoxins
Banci, L
Bertini, I
Savellini, GG
Luchinat, C
[J]. INORGANIC CHEMISTRY, 1996, 35 (14) : 4248 - 4253
[3] PH-LINKED CONFORMATIONAL REGULATION OF A METALLOPROTEIN OXIDATION REDUCTION EQUILIBRIUM - ELECTROCHEMICAL ANALYSIS OF THE ALKALINE FORM OF CYTOCHROME-C
BARKER, PD
MAUK, AG
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (10) : 3619 - 3624
[4] Are unit charges always negligible?
Bertini, I
GoriSavellini, G
Luchinat, C
[J]. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 1997, 2 (01): : 114 - 118
[5] BRANDT KG, 1966, J BIOL CHEM, V241, P4180
[6] BRAYER GD, 1996, CYTOCHROME C MULTIDI, P103
[7] CHOTHIA C, 1984, ANNU REV BIOCHEM, V53, P537
[8] OXIDATION-REDUCTION POTENTIAL MEASUREMENTS OF CYTOCHROME-C PEROXIDASE AND PH DEPENDENT SPECTRAL TRANSITIONS IN FERROUS ENZYME
CONROY, CW
TYMA, P
DAUM, PH
ERMAN, JE
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1978, 537 (01) : 62 - 69
[9] CREIGHTON RE, 1993, PROTEINS STRUCTURE A, P154
[10] ROLE OF ARGININE-38 IN REGULATION OF THE CYTOCHROME-C OXIDATION-REDUCTION EQUILIBRIUM
CUTLER, RL
DAVIES, AM
CREIGHTON, S
WARSHEL, A
MOORE, GR
SMITH, M
MAUK, AG
[J]. BIOCHEMISTRY, 1989, 28 (08) : 3188 - 3197

← 1 2 3 4 5 6 →