Control of metalloprotein redox potentials: What does site-directed mutagenesis of hemoproteins tell us?

被引：112

作者：

Mauk, AG

Moore, GR

机构：

[1] UNIV E ANGLIA,SCH CHEM SCI,CTR METALLOPROT SPECT & BIOL,NORWICH NR4 7TJ,NORFOLK,ENGLAND

[2] UNIV BRITISH COLUMBIA,DEPT BIOCHEM,VANCOUVER,BC V6T 1W5,CANADA

来源：

JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY | 1997年 / 2卷 / 01期

关键词：

redox potentials; hemoproteins; electrostatic interactions;

D O I：

10.1007/s007750050115

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

An overview of factors affecting metalloprotein redox potentials is given, together with an assessment of the role of site-directed mutagenesis of hemoproteins in investigating this topic and a description of several theoretically challenging hemoproteins. The conclusion is reached that a quantitative and experimentally testable description of metalloprotein redox potentials is not yet available.

引用

页码：119 / 125

页数：7

共 51 条

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