PNIPAM Gel-Coated Gold Nanorods, for Targeted Delivery Responding to a Near-Infrared Laser

被引：223

作者：

Kawano, Takahito ^{[1
]}

Niidome, Yasuro ^{[1
]}

Mori, Takeshi ^{[1
,2
]}

Katayama, Yoshiki ^{[1
,2
,3
]}

Niidome, Takuro ^{[1
,2
,4
]}

机构：

[1] Kyushu Univ, Dept Appl Chem, Fac Engn, Nishi Ku, Fukuoka 8190395, Japan

[2] Kyushu Univ, Ctr Future Chem, Nishi Ku, Fukuoka 8190395, Japan

[3] Japan Sci & Technol Agcy, CREST, Kawaguchi, Saitama 3320012, Japan

[4] Japan Sci & Technol Agcy, PRESTO, Kawaguchi, Saitama 3320012, Japan

来源：

BIOCONJUGATE CHEMISTRY | 2009年 / 20卷 / 02期

基金：

日本科学技术振兴机构;

关键词：

PHASE-TRANSITION; DRUG-DELIVERY; ASPECT RATIO; NANOTECHNOLOGY; TEMPERATURE; CANCER; LIGHT; NANOPARTICLES; DEPENDENCE; MICROGELS;

D O I：

10.1021/bc800480k

中图分类号：

Q5 [生物化学];

学科分类号：

070307 [化学生物学];

摘要：

Gold nanorods can be used as photothermal converters, permitting near-infrared (NIR) light to be transmitted deep into tissues without causing damage. We prepared hybrid nanorods with a core-shell structure, i.e., a single gold nanorod encapsulated in a poly (N-isopropylacrylamide) nanogel. Hybrid nanorods demonstrated remote, reversible, pulsatile phase transition and in vivo action after irradiation using a NIR laser.

引用

页码：209 / 212

页数：4

共 33 条

[1]

ON OFF THERMOCONTROL OF SOLUTE TRANSPORT .1. TEMPERATURE-DEPENDENCE OF SWELLING OF N-ISOPROPYLACRYLAMIDE NETWORKS MODIFIED WITH HYDROPHOBIC COMPONENTS IN WATER [J].