Hepatitis B virus genotypes in Mongols and Australian aborigines

被引：28

作者：

Alestig, E ^{[1
]}

Hannoun, C ^{[1
]}

Horal, P ^{[1
]}

Lindh, M ^{[1
]}

机构：

[1] Gothenburg Univ, Dept Clin Virol, S-41346 Gothenburg, Sweden

来源：

ARCHIVES OF VIROLOGY | 2001年 / 146卷 / 12期

关键词：

D O I：

10.1007/s007050170005

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Hepatitis B virus (HBV) is spread worldwide. Seven genotypes, A-G, have been described, differing by more than 8% of the genome. In eastern Asia and Oceania genotypes B and C are predominant. However, little is known about genotypes in Mongolia and Australian aborigines. We analysed the preS and S regions of HBV from 9 Mongols and 5 Australian Aborigines. All Mongolian strains were of genotype D and were most similar to Central Asian sequences. All the Australian strains were genetically of serotype ayw3, and could not be reliably classified by the S region analysis, but placed on a separate branch. By preS analysis, they were however clearly of genotype C. The 6-7% nucleotide difference from published Asian genotype C sequences suggests that they diverged from Asian genotype C branch more than 1000 years ago.

引用

页码：2321 / 2329

页数：9